Results 51 to 60 of about 16,032 (244)

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Assessment of individual muscle hardness and stiffness using ultrasound elastography

Journal of Physical Fitness and Sports Medicine, 2016
Assessing muscle mechanical properties such as hardness and stiffness has important clinical implications. The use of ultrasound elastography to assess individual muscle hardness or stiffness has been increasing in recent years.
Takayuki Inami, Yasuo Kawakami
doaj   +1 more source

Diagnostic accuracy of shear wave elastography in evaluating renal fibrosis in children with chronic kidney disease: a comparative study with nuclear scan

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Chronic kidney disease (CKD) is a significant health issue in pediatric patients due to fibrosis progression. Shear wave elastography (SWE) is a noninvasive technique used to assess fibrosis in CKD, but its efficacy needs to be better ...
Abhishek Kumar Yadav, Poonam Sherwani, Enono Yhoshu, Vandana Kumar Dhingra, Nowneet Kumar Bhat   +4 more
doaj   +1 more source

Two-dimensional shear wave elastography and ultrasound-guided attenuation parameter for progressive non-alcoholic steatohepatitis.

PLoS ONE, 2021
Background and aimsWe investigated the usefulness of combining two-dimensional shear wave elastography and the ultrasound-guided attenuation parameter for assessing the risk of progressive non-alcoholic steatohepatitis, defined as non-alcoholic ...
Hidekatsu Kuroda, Yudai Fujiwara, Tamami Abe, Tomoaki Nagasawa, Takuma Oguri, Sachiyo Noguchi, Naohisa Kamiyama, Yasuhiro Takikawa   +7 more
doaj   +1 more source

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

Advanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao, Lisa‐Marie Skrip, Heiko Tzschätzsch, Tom Meyer, Hossein S. Aghamiry, Alexander Arnold, Lene Änne Böhne, Jakob Jordan, Oliver Boehm, Agnes K. Boehm, Steffen Görner, Jakob Schattenfroh, Yanglei Wu, Pedro Augusto Dantas de Moraes, Johann Pratschke, Jürgen Braun, Igor M. Sauer, Jing Guo, Ingolf Sack, Karl H. Hillebrandt   +19 more
wiley   +1 more source

Shear wave elastography of the ulnar nerve at the forearm

Medicine, 2021
Abstract The study included 38 ulnar nerves in 20 healthy subjects. High-resolution ultrasound and Shear wave elastography were used to evaluate the ulnar nerve at the mid forearm. The mean cross-sectional area of the ulnar nerve was 7.1 mm2. The mean shear elastic modulus of the nerve in the short axis was 27.4 kPa.
Bedewi, Mohamed Abdelmohsen, Kotb, Mamdouh A., Aldossary, Nasser M., Abodonya, Ahmed M., Alhariqi, Bader A., Swify, Sherine Mohamed   +5 more
openaire   +2 more sources

New aspects in shear-wave elastography of prostate cancer

, 2015
Aim: This study was designed to evaluate the performance of shear-wave elastography as a diagnostic tool for prostate cancer in a larger cohort of patients than previously reported.
Liehr, Uwe-Bernd, Schostak, Martin, Jakob Wendler, Johann, Wendler, Johann Jakob, Porsch, Markus, Maciej Pech, Markus Porsch, Lux, Anke, Johann Jakob Wendler, Anke Lux, Martin Schostak, Pech, Maciej, Uwe-Bernd Liehr   +12 more
core   +1 more source

Dual-Probe Shear Wave Elastography in a Transversely Isotropic Phantom [PDF]

, 2022
This project aimed to evaluate the possibility of obtaining a full mechanical characterization of a transversely isotropic (TI) phantom with dual-probe SWE. A TI phantom was developed and mechanical tests were performed to verify its anisotropy. Moreover,
Bassan, Gioia
core  

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

Shear wave elastography of the pancreas: impact of Type 2 Diabetes on pancreatic tissue stiffness

The Egyptian Journal of Radiology and Nuclear Medicine
Background Shear Wave elastography (SWE) is a non-invasive tool that measures the degree of tissue stiffness in organs such as the thyroid, liver and breast. There are few studies evaluating the usefulness of shear wave elastography of the pancreas.
Rafik A. Elias, Khaled Sayed Soliman, Ahmed Fathy Al-Asmar   +2 more
doaj   +1 more source