Results 161 to 170 of about 309,304 (235)

Atomic‐Level Strain Sensing and Piezoresistance Effect in a 1D Single‐Atom Chain

open access: yesAdvanced Science, EarlyView.
The atomic‐scale piezoresistance effect of the Ag single‐atom chain is explored using strain characterization and electrical measurement. Single‐atom chain has the potential to serve as a strain sensor with atomic‐level precision, overcoming the challenge of low temporal resolution in a transmission electron microscope.
Zhi Qu   +6 more
wiley   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen   +13 more
wiley   +1 more source

Achieving High Damping Capacity in Oxygen‐Enhanced BCC Zr‐Hf‐Ti‐Nb Multi‐Principal‐Element Alloys with Low Young's Modulus

open access: yesAdvanced Science, EarlyView.
A series of oxygen‐enhanced Zr‐Hf‐Ti‐Nb MPEAs with high strength and outstanding damping capacity are developed through tailoring the BCC structural stability by an elaborate composition regulation. Strengthening mechanism for high strength and damping mechanism related to various Snoek‐type relaxations reveals that the existence of multiple separate O‐
Qing Wang   +10 more
wiley   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

open access: yesAdvanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack   +22 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

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