Results 241 to 250 of about 347,338 (355)

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration

open access: yesAdvanced Science, EarlyView.
This study reveals that Kdm6a plays key roles in repressing either peripheral nervous system (PNS) or central nervous system (CNS) axon regeneration, whereas Kdm6b is not involved in regulating CNS axon regeneration. Moreover, both demethylases are able to regulate CNS neuronal survival after injury, but with non‐overlapping mechanisms.
Shu‐Guang Yang   +13 more
wiley   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

open access: yesAdvanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi   +7 more
wiley   +1 more source

Elastic Relaxation of Coherent InGaN/GaN Interfaces at the Microwire LED Sidewall

open access: yesAdvanced Science, EarlyView.
Strain mapping and modeling reveal that the interfacial shear stresses arise toward the traction free sidewall of microscale light emitting diode (LED) wires while the two complementary strained InGaN and GaN layers in multiple quantum wells are relaxed to revert their bulk lattice parameters near the sidewall.
Jongil Kim   +5 more
wiley   +1 more source

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