Results 31 to 40 of about 131,338 (245)
Shedding light on GPIbα shedding
Current Opinion in HematologyPurpose of review Ectodomain shedding has been investigated since the late 1980s. The abundant and platelet specific GPIbα receptor is cleaved by ADAM17 resulting in the release of its ectodomain called glycocalicin. This review will address the role of glycocalicin as an end-stage marker of platelet turnover and storage lesion
Debaene, Caitlin +2 more
openaire +3 more sources
Shedding of APP limits its synaptogenic activity and cell adhesion properties
Frontiers in Cellular Neuroscience, 2014 The Amyloid precursor protein (APP) plays a central role in Alzheimer’s disease (AD) and has essential synapse promoting functions. Synaptogenic activity as well as cell adhesion properties of APP presumably depend on trans-cellular dimerization via its ...
Ronny eStahl +9 more
doaj +1 more source
Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania. [PDF]
, 2013 To compare the presence and quantity of cervicovaginal HIV among HIV seropositive women with clinical herpes, subclinical HSV-2 infection and without HSV-2 infection respectively; to evaluate the association between cervicovaginal HIV and HSV shedding ...
Riedner, Gabriele +48 more
core +1 more source
Influence of age, severity of infection, and co-infection on the duration of respiratory syncytial virus (RSV) shedding [PDF]
, 2015 RSV is the most important viral cause of pneumonia and bronchiolitis in children worldwide and has been associated with significant disease burden. With the renewed interest in RSV vaccines, we provide realistic estimates on duration, and influencing ...
Agoti, Charles N. +7 more
core +1 more source
Modeling Wet-Snow Shedding from Current-Carrying Conductors [PDF]
The initiation of wet-snow shedding from currentcarrying conductors was studied experimentally and theoretically. A suspended cable with cylindrical snow accretion was considered, and some of the snow properties at the end of sleeve were measured and ...
Kollar, László E. +3 more
core +3 more sources
RodriguésiaResumo Estudos fenológicos auxiliam na compreensão do comportamento das espécies em resposta a alterações no ambiente e são também importantes para a conservação e manejo das mesmas. A fenologia de Paratecoma peroba (Record & Mell) Kuhlm. foi estudada no
Beatriz Lacerda Almeida Lins +1 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigation into the Strouhal numbers associated with vortex shedding from parallel-plate thermoacoustic stacks in oscillatory flow conditions [PDF]
, 2010 This paper investigates vortex shedding processes occurring at the end of a stack of parallel plates, due to an oscillating flow induced by an acoustic standing wave.
Yu, Z. +11 more
core +1 more source
Vaccines, 2023 Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the assessment of subject safety, quality and efficacy aspects of medicinal products for human use, genetically ...
Sheela Onnockx +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source