Results 71 to 80 of about 131,338 (245)

Vortex shedding from tapered, triangular plates: taper and aspect ratio effects

, 2004
Further experiments on features of the vortex shedding from tapered flat plates normal to an airstream are described. The work extends that of Castro and Rogers (2002) and concentrates on the study of the effects of varying the spanwise aspect ratio for ...
Lee Watson, Ian P. Castro, Watson, Lee, Castro, Ian P.   +3 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The sheddase ADAM10 is a potent modulator of prion disease

eLife, 2015
The prion protein (PrPC) is highly expressed in the nervous system and critically involved in prion diseases where it misfolds into pathogenic PrPSc.
Hermann C Altmeppen, Johannes Prox, Susanne Krasemann, Berta Puig, Katharina Kruszewski, Frank Dohler, Christian Bernreuther, Ana Hoxha, Luise Linsenmeier, Beata Sikorska, Pawel P Liberski, Udo Bartsch, Paul Saftig, Markus Glatzel   +13 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Allele-specific interactions between CAST AWAY and NEVERSHED control abscission in Arabidopsis flowers

Frontiers in Plant Science, 2016
An advantage of analyzing abscission in genetically tractable model plants is the ability to make use of classic genetic tools such as suppression analysis.
William D. Groner, Megan E. Christy, Catherine M. Kreiner, Sarah J. Liljegren   +3 more
doaj   +1 more source

Shedding and extensive and prolonged environmental contamination of goat farms of Q fever patients by Coxiella burnetii

Veterinary Medicine and Science, 2022
Background A majority (>70%) of Q fever patients in South Korea do not have a history of animal contact. Therefore, unconscious environmental exposure is suspected.
Hyeon Seop Byeon, Stalin Nattan, Jun Hyoung Kim, Seong Tae Han, Mun Hui Chae, Mi Na Han, Byeongwoo Ahn, Yong‐Dae Kim, Hee‐Sung Kim, Hye Won Jeong   +9 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Wake states and frequency selection of a streamwise oscillating cylinder [PDF]

, 2013
This paper presents the results of an in-depth study of the flow past a streamwise oscillating cylinder, examining the impact of varying the amplitude and frequency of the oscillation, and the Reynolds number of the incoming flow.
Leontini, Justin S., Lo Jacono, David, Thompson, Mark C.   +2 more
core   +1 more source

Efficacy of Three Vaccine Regimens Against Infectious Hematopoietic Necrosis Virus Transmission Potential in Rainbow Trout

Vaccines
Background: Vaccination is often a highly effective approach for protecting against clinical disease and mortality caused by viruses. However, vaccine efficacy against viral transmission has rarely been assessed, which can provide vital information on ...
Juliette Doumayrou, Mary G. Frazier, Hannah N. Brown, Andrew R. Wargo   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source