Results 121 to 130 of about 1,218,515 (306)

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

A discussion of norms for S supply in organic farming based on content in forage and ruminant performance in Norway [PDF]

open access: yes, 2008
The content of sulphur (S) in grassland on 27 Norwegian organic farms with dairy or sheep production was investigated in 2001 and 2002. The forage content of S was below the norms (2 g S kg DM-1) for both plants and animals in a large proportion of the ...
Bakken, Anne Kjersti, Hansen, Sissel
core  

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman   +1 more
wiley   +1 more source

Matthew 25:31-46 Exegetical Perspective

open access: yes, 2013
Excerpt: The parable of the Sheep and the Goats is one of the most moving, yet most vexing among the teachings of Jesus. Found only in Matthew, this parable concludes its final collection of Jesus\u27 sayings in ways striking and disturbing.
Anderson, Paul N.
core  

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

Prevalence of chlamydiae in dairy cattle herds and factors contributing to the spread of infections

open access: yesJournal of Veterinary Research
Different Chlamydia species affect cattle and contribute to economic losses. One of them, C. pecorum, is a globally endemic livestock pathogen. Despite its endemicity, prevalence data from Poland have so far been limited.
Szymańska-Czerwińska Mońika   +4 more
doaj   +1 more source

Wireless blood pressure sensor implantation in sheep: A detailed technique

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer   +10 more
wiley   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu   +5 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

open access: yesAdvanced NanoBiomed Research, EarlyView.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani   +4 more
wiley   +1 more source

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