Results 31 to 40 of about 113,236 (255)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Small Ruminant Farming in Tribal Areas of Dera Ghazi Khan, Punjab, Pakistan

open access: yesVeterinary Sciences, 2022
Provincially Administered Tribal Areas (PATA) of Punjab-Pakistan are comprised of hilly mountains with small ruminants as a sole source of income. In this study, farming practices, productivity, health and the economic value of sheep were evaluated in ...
Muhammad Ameen Jamal   +12 more
doaj   +1 more source

Polydopamine‐Wool Textiles for Sustainable Interfacial Solar Vapor Generation

open access: yesAdvanced Science, EarlyView.
A natural wool textile engineered for high solar absorbance and a fast‐wicking structure serves as a highly efficient, single‐layer system for interfacial solar vapor generation (ISVG). This integrated evaporator seamlessly couples rapid water transport with continuous evaporation. Ultimately, this sustainable photothermal design offers a scalable, eco‐
Kyuin Park   +6 more
wiley   +1 more source

The Bighorn Habitat Assessment Tool: A Method to Quantify Conservation Value on Landscapes Impacted by Mining

open access: yesLand, 2022
We present a methodology to assess the conservation value of mitigation lands for desert bighorn sheep (Ovis canadensis nelsoni) within landscapes impacted by historic and ongoing industrial uses.
Dayan J. Anderson   +2 more
doaj   +1 more source

Evaluating the welfare of extensively managed sheep

open access: yesPLOS ONE, 2019
The aim of this study was to identify the main on-farm welfare issues likely to be encountered in extensive sheep farming systems. Thirty-two commercial sheep farms in Victoria, Australia were involved in this study. Of the 32 farms involved, 30 were visited twice (at mid-pregnancy and weaning), and 2 farms only once (both at weaning).
Carolina A. Munoz   +3 more
openaire   +5 more sources

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

open access: yesAdvanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou   +17 more
wiley   +1 more source

The Effect of Comic Book’s Story Character and Color on Farmers’ Knowledge Gain About Small Sheep Farm Management in Kulur, District of Majalengka, West Java, Indonesia

open access: yesMedia Peternakan, 2009
What kind of comic book’s character was best suited to small sheep farmers, what was their preferred color, and what were the combined effects of such characters and color on the farmers’ knowledge about small sheep farm management?
S. R. Satmoko, A. Jahi
doaj  

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

High-Density Genomic Characterization of Native Croatian Sheep Breeds

open access: yesFrontiers in Genetics, 2022
A recent comprehensive genomic analysis based on 50K SNP profiles has shown that the regional Balkan sheep populations have considerable genetic overlap but are distinctly different from surrounding breeds.
Ivana Drzaic   +9 more
doaj   +1 more source

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