Results 51 to 60 of about 14,089 (308)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Development of a Device Compatible with Universal Testing Machine to Perform Hole Expansion and Erichsen Cupping Tests

open access: yesMachines, 2019
The material characterization regarding sheet metal formability is usually assessed by the forming limit curve (FLC). The FLC requires specialized and expensive equipment, several samples with different geometries, and can be a very time-consuming ...
Rafael O. Santos   +5 more
doaj   +1 more source

Strain localization analysis using a multiscale model [PDF]

open access: yes, 2007
In order to analyze the formability of steels in sheet metal forming, a ductility loss criterion is coupled with a multiscale model. The behavior at the mesoscopic (grain) scale is modeled by a large strain micromechanical constitutive law, which is then
ABED-MERAIM, Farid   +4 more
core   +8 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Forming Process Analysis of an AA6060 Aluminum Vessel [PDF]

open access: yesFracture and Structural Integrity, 2018
This work analyses the results of a simple forming process of an AA6060 aluminium alloy sheet in order to validate the development of a simulation model based on the finite element method (FEM).
Gillo Giuliano   +3 more
doaj   +2 more sources

Experimental and Numerical Assessment of the Hot Sheet Formability of Martensitic Stainless Steels

open access: yesJournal of Manufacturing and Materials Processing, 2020
Hot formed sheet components made of Martensitic Stainless Steels (MSS) can achieve ultra-high strengths in combination with very high corrosion resistance.
Peter Birnbaum   +5 more
doaj   +1 more source

Epidemiological and awareness study of tuberculosis in Batu Pahat, Johor, Malaysia [PDF]

open access: yes, 2014
Tuberculosis (TB) remains one of the serious infectious diseases and has been characterized worldwide as an epidemic by World Health Organization (WHO). TB is still a public health problem in Malaysia.
Sanusi, Shuaibu Babaji
core  

Knowledge based cloud FE simulation of sheet metal forming processes [PDF]

open access: yes, 2016
The use of Finite Element (FE) simulation software to adequately predict the outcome of sheet metal forming processes is crucial to enhancing the efficiency and lowering the development time of such processes, whilst reducing costs involved in trial-and ...
El Fakir, O   +8 more
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Investigation of the deformation stability in the incremental sheet forming process

open access: yesMATEC Web of Conferences, 2015
Incremental sheet forming (ISF) is a highly versatile and flexible process for rapid manufacturing of complex sheet metal parts. One of the unique characters of the ISF process is the improved formability comparing to conventional sheet forming process ...
Ai S., Lu B., Long H., Chen J., Ou H.
doaj   +1 more source

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