Results 51 to 60 of about 1,279,444 (349)

Reliability modeling of a 1-out-of-2 system: Research with diverse Off-the-shelf SQL database servers [PDF]

open access: yes, 2007
Fault tolerance via design diversity is often the only viable way of achieving sufficient dependability levels when using off-the-shelf components. We have reported previously on studies with bug reports of four open-source and commercial off-the-shelf ...
Bishop, P. G.   +3 more
core   +1 more source

Cross-Shelf Exchange [PDF]

open access: yesAnnual Review of Marine Science, 2016
Cross-shelf exchange dominates the pathways and rates by which nutrients, biota, and materials on the continental shelf are delivered and removed. This follows because cross-shelf gradients of most properties are usually far greater than those in the alongshore direction.
openaire   +2 more sources

Patterns of growth, mortality, and size of the tropical damselfish Acanthochromis polyacanthus across the continental shelf of the Great Barrier Reef [PDF]

open access: yes, 2005
Age-based analyses were used to demonstrate consistent differences in growth between populations of Acanthochromis polyacanthus (Pomacentridae) collected at three distance strata across the continental shelf (inner, mid-, and outer shelf) of the central
Hughes, Julian M., Kingsford, Michael J.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Grounding of an Ice Shelf in the Central Arctic Ocean: A Modeling Experiment [PDF]

open access: yes, 2003
A numerical ice sheet model was used in a first test towards evaluating the hypothesis that, during a period of large-scale glaciation, an ice shelf emanating from the Barents/Kara Seas grounded across parts of the Lomonosov Ridge to a depth of around ...
Jakobsson, Martin   +2 more
core   +1 more source

Dynamics of wind-driven upwelling and relaxation between Monterey Bay and Point Arena: Local-, regional-, and gyre-scale controls [PDF]

open access: yes, 2009
In north and central California, equatorward winds drive equatorward flows and the upwelling of cold dense water over the shelf during the midspring and summer upwelling season.
Dever, Edward P, Pringle, James M.
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Projecting Antarctica's contribution to future sea level rise from basal ice shelf melt using linear response functions of 16 ice sheet models (LARMIP-2)

open access: yesEarth System Dynamics, 2019
. The sea level contribution of the Antarctic ice sheet constitutes a large uncertainty in future sea level projections. Here we apply a linear response theory approach to 16 state-of-the-art ice sheet models to estimate the Antarctic ice sheet ...
A. Levermann   +36 more
semanticscholar   +1 more source

Unique Performance Considerations for Printable Organic Semiconductor and Perovskite Radiation Detectors: Toward Consensus on Best Practice Evaluation

open access: yesAdvanced Functional Materials, EarlyView.
A lack of standard approaches for testing and reporting the performance of metal halide perovskites and organic semiconductor radiation detectors has resulted in inconsistent interpretation of performance parameters, impeding progress in the field. This Perspective recommends key metrics and experimental details, which are suggested for reporting in ...
Jessie A. Posar   +8 more
wiley   +1 more source

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