Results 61 to 70 of about 12,216 (264)
Recent Progress in Analytical SHG Spectroscopy
Analytical Sciences, 1998 The progress of laser technology has brought extensive applications of nonlinear optical (NLO) spectroscopy to analytical fields. Especially, optical second harmonic generation (SHG), which is one of the most popular NLO phenomena, has been successfully applied to the study of interfaces (surfaces).
YAMADA, Sunao, LEE, I-Yin Sandy
openaire +2 more sources
Advanced Science, EarlyView.Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Multimodal two-photon imaging using a second harmonic generation-specific dye
Nature Communications, 2016 Current dyes for second harmonic generation (SHG) imaging strongly fluoresce, limiting their application. Here the authors develop a SHG-specific dye, Ap3, that partitions into cell membranes, displays sensitivity to membrane potential and has virtually ...
Mutsuo Nuriya +5 more
doaj +1 more source
Advanced Science, EarlyView.Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source
Advanced Science, EarlyView.This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun +14 more
wiley +1 more source
Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond
Advanced Science, EarlyView.Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu +5 more
wiley +1 more source
Advanced Science, EarlyView.A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
wiley +1 more source
New chalcone compound exhibits microrna-mediated anticancer properties in glioblastoma.
PLoS ONEBackgroundTherapy-resistant glioblastoma constitutes the most lethal adult brain malignancy, bearing extremely poor patients' prognosis. Combinational therapies are accompanied by severe side effects and significant financial burden, highlighting the ...
Denis Mustafov +7 more
doaj +1 more source
Advanced Science, EarlyView.Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu +7 more
wiley +1 more source
Engineering a genetically-encoded SHG chromophore by electrostatic targeting to the membrane
Frontiers in Molecular Neuroscience, 2014 Although second harmonic generation (SHG) microscopy provides unique imaging advantages for voltage imaging and other biological applications, genetically-encoded SHG chromophores remain relatively unexplored.
Yuka eJinno +7 more
doaj +1 more source