Results 181 to 190 of about 2,377 (196)

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

open access: yesAngewandte Chemie, EarlyView.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito   +9 more
wiley   +2 more sources

Myelitis‐Predominant Aggressive Phenotype: Unveiling Unique Patterns of Late‐Onset Neuromyelitis Optica Spectrum Disorders

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare clinical features and prognosis of late‐onset neuromyelitis optica spectrum disorder (LO‐NMOSD, onset age ≥60 years) with adult‐onset NMOSD (AO‐NMOSD, onset age 18–59 years), and to provide insights for individualized management in elderly patients.
Ya‐Lan Pu   +15 more
wiley   +1 more source

Atroposelective Suzuki–Miyaura Coupling to Form 2‐Amino‐2′‐Hydroxybiphenyls Enabled by sRuPhos

open access: yesAngewandte Chemie, EarlyView.
We report a new chiral phosphine ligand, sRuPhos, which permits the highly enantioselective Suzuki–Miyaura coupling of ortho‐aniline and ortho‐phenol building blocks. This results in 2‐amino‐2′‐hydroxybiphenyls with very high enantiomeric excesses, products that will have application in pharmaceutical synthesis and ligand design for catalysis ...
Hamzah Sharif   +3 more
wiley   +2 more sources

Micro/Nanorobot for Drug Delivery—A Review of Material Selections

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley   +1 more source

Between Order and Confusion: Clearing up Structural Misconceptions in Carbon Materials Nomenclature

open access: yesAngewandte Chemie International Edition, EarlyView.
Despite the versatile use of carbon materials, inconsistent terminology and inadequate characterization – especially regarding graphene structures based on sp2‐hybridized carbon atoms – often cause confusion. This perspective clarifies terms like graphite, graphitic carbon, non‐graphitic carbon, and amorphous carbon by aligning IUPAC definitions with X‐
Chantal Glatthaar   +3 more
wiley   +1 more source

Research Status and Development Trend of Macromolecular Structure and Model Construction of Different Coals

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Coal is a natural macromolecular substance composed of complex organic molecules and a small amount of minerals. Its chemical composition and microstructure are highly complex and variable, and no unified definition exists. This inherent structural complexity underscores the theoretical significance of constructing accurate macromolecular ...
Chao Zhou   +5 more
wiley   +1 more source

Numerical and Experimental Study of Mixing Characteristics in a Spiral Micromixer

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Significant enhancement of mixing performance can be achieved by Dean vortices in spiral channels. In order to deeply explore the mixing mechanisms and variation laws in spiral micromixers, this work designed a spiral micromixer and adopted a combined method of experiments and numerical simulations to analyze the mixing performance and ...
Anming Yang, Shiqing Zheng
wiley   +1 more source

Energy‐Efficient and Sustainable Design Optimization for Ternary Mixture Separation: A Comparative Analysis of Sequential Iterative Optimization and Non‐Dominated Sorting Genetic Algorithm II

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study presents a comparative analysis of two optimization approaches: Sequential Iterative Optimization (SIO) and Non‐dominated Sorting Genetic Algorithm II (NSGA‐II) applied to the separation of ternary mixtures (1‐butanol, isobutanol, and 2‐butanol) using Dual‐Column Distillation (DCD) and Dividing‐Wall Column (DWC) processes. Through a
Ruijie Wang   +5 more
wiley   +1 more source

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