Results 181 to 190 of about 2,377 (196)
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito +9 more
wiley +2 more sources
Objective The objective of this study was to compare clinical features and prognosis of late‐onset neuromyelitis optica spectrum disorder (LO‐NMOSD, onset age ≥60 years) with adult‐onset NMOSD (AO‐NMOSD, onset age 18–59 years), and to provide insights for individualized management in elderly patients.
Ya‐Lan Pu +15 more
wiley +1 more source
Atroposelective Suzuki–Miyaura Coupling to Form 2‐Amino‐2′‐Hydroxybiphenyls Enabled by sRuPhos
We report a new chiral phosphine ligand, sRuPhos, which permits the highly enantioselective Suzuki–Miyaura coupling of ortho‐aniline and ortho‐phenol building blocks. This results in 2‐amino‐2′‐hydroxybiphenyls with very high enantiomeric excesses, products that will have application in pharmaceutical synthesis and ligand design for catalysis ...
Hamzah Sharif +3 more
wiley +2 more sources
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
Between Order and Confusion: Clearing up Structural Misconceptions in Carbon Materials Nomenclature
Despite the versatile use of carbon materials, inconsistent terminology and inadequate characterization – especially regarding graphene structures based on sp2‐hybridized carbon atoms – often cause confusion. This perspective clarifies terms like graphite, graphitic carbon, non‐graphitic carbon, and amorphous carbon by aligning IUPAC definitions with X‐
Chantal Glatthaar +3 more
wiley +1 more source
ABSTRACT Coal is a natural macromolecular substance composed of complex organic molecules and a small amount of minerals. Its chemical composition and microstructure are highly complex and variable, and no unified definition exists. This inherent structural complexity underscores the theoretical significance of constructing accurate macromolecular ...
Chao Zhou +5 more
wiley +1 more source
Numerical and Experimental Study of Mixing Characteristics in a Spiral Micromixer
ABSTRACT Significant enhancement of mixing performance can be achieved by Dean vortices in spiral channels. In order to deeply explore the mixing mechanisms and variation laws in spiral micromixers, this work designed a spiral micromixer and adopted a combined method of experiments and numerical simulations to analyze the mixing performance and ...
Anming Yang, Shiqing Zheng
wiley +1 more source
ABSTRACT This study presents a comparative analysis of two optimization approaches: Sequential Iterative Optimization (SIO) and Non‐dominated Sorting Genetic Algorithm II (NSGA‐II) applied to the separation of ternary mixtures (1‐butanol, isobutanol, and 2‐butanol) using Dual‐Column Distillation (DCD) and Dividing‐Wall Column (DWC) processes. Through a
Ruijie Wang +5 more
wiley +1 more source

