Results 121 to 130 of about 800,089 (361)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

GEO-ENERGETICS OF UKRAINIAN SHIELD [PDF]

open access: yes, 2018
The analysis and systematization of geodynamic conditions of underground mining of ore deposits in Ukraine is executed.
KHOMENKO, Oleh   +9 more
core  

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Nanodiamond‐Infused Microgels for pH‐Tunable Rheology, Lubrication, and UV Protection

open access: yesAdvanced Functional Materials, EarlyView.
Microgels consisting of swollen polyacrylic acid polymer networks, impregnated with nanodiamonds provide protection from ultraviolet (UV) radiation harmful to human health. Nanodiamonds enable UV blockage and control of the rheology (flow) and lubrication (skin‐feel) of these microgel‐skincare‐mimics.
Pallav K. Jani   +10 more
wiley   +1 more source

Shields in Vaccination [PDF]

open access: yesJournal of the American Medical Association, 1914
To the Editor: —Will you give me space inThe Journalin which to protest against the still too frequent use of "shields" in covering vaccination wounds? In routine vaccination work it has recently been my lot to examine many arms, a number of which I have dressed after the persons had applied shields, on their own initiative, or often on the advice of ...
openaire   +2 more sources

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

Stability Study of Shield Tunnel Excavation Face Induced by Shield Chamber Pressure Entering in Shallow-Buried Sand Stratum

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Solve the problem of excavation surface stability during shield tunneling with pressure entry in shallow-buried sandy stratum.To solve the problem of the stability of tunnel face of shield tunnel with pressure into the chamber in shallow ...
GE Jun
doaj   +1 more source

Muck Problems in Subway Shield Tunneling in Sandy Cobble Stratum

open access: yesPolish Maritime Research, 2016
Experiments aiming at the muck improvement for Chengdu’s subway shield tunneling in water-rich sandy cobble ground initially finds out the kinds and ratio of muck improver suitable for the this strata, and through the field application determines the ...
Cui Kai, Lin Weikang
doaj   +1 more source

Britannia’s Shield: Lieutenant-General Sir Edward Hutton and Late-Victorian Imperial Defence (Book Review) by Craig Stockings [PDF]

open access: yes, 2017
Review of Britannia’s Shield: Lieutenant-General Sir Edward Hutton and Late-Victorian Imperial Defence by Craig ...
Wood, James
core   +1 more source

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