Results 191 to 200 of about 328,347 (250)

‘I'd rather have worse gums than worse lungs’: Young people's views of nicotine pouches in the UK

open access: yesAddiction, EarlyView.
Abstract Background and aims Nicotine pouches entered the UK market in 2019. Although research has shown that young people's prevalence of use has been low, it has been reported to be increasing and a cause for concern. This paper reports the findings of the first qualitative study in the UK to explore the views of 14–16 year olds' knowledge, awareness
Andy MacGregor   +7 more
wiley   +1 more source

Prevention and Management of Driveline Infections in Ventricular Assist Device Patients: The DESTINE 2.0 Staging Proposal and Expert Recommendations

open access: yesArtificial Organs, EarlyView.
DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt   +7 more
wiley   +1 more source

Palaeoenvironmental and climatic changes from the lateglacial of the Saalian to the Late Weichselian in central Poland: a multiproxy study from Józefów

open access: yesBoreas, EarlyView.
Józefów site is a case study which provides a detailed record of environmental and climate changes and confirms the main traces of the landscape morphogenesis of the Late Pleistocene established in central‐eastern Europe. This study presents a multiproxy reconstruction of palaeoenvironment under variable climatic conditions from the retreat of the ...
Aleksandra Majecka   +11 more
wiley   +1 more source

Unravelling the phylogeny of armadillos and their kin (Mammalia, Xenarthra, Cingulata) combining morphological, molecular, and stratigraphic data

open access: yesCladistics, EarlyView.
Abstract Cingulata, a major lineage of Xenarthra, comprises extinct and extant armoured placental mammals that diversified throughout the Cenozoic. Despite extensive study, phylogenetic hypotheses based on morphological and molecular data remain incongruent, and no total evidence analysis has been conducted. Here, we integrate the largest morphological
Daniel M. Casali   +7 more
wiley   +1 more source

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

open access: yesThe FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti   +8 more
wiley   +1 more source

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