Results 181 to 190 of about 1,859 (209)

Influence of N‐Functionalization of Amiridine on the Biological Activity of Its Conjugates as Multitarget Agents for Potential Treatment of Alzheimer's Disease

open access: yesChemMedChem, Volume 21, Issue 14, 29 July 2026.
New conjugates of amiridine and salicylimine/amine with an N‐acylalkylene spacer were synthesized. N‐acylation of amiridine conjugates leads to a decrease in their protonation, resulting in a substantial reduction in anticholinesterase activity and relative inability to block Aβ42 self‐aggregation compared to previously studied analogs with an N ...
Galina F. Makhaeva   +14 more
wiley   +1 more source

Stabilizing the Hexacyanotrimethylenecyclopropane Electron Acceptor—Structural and Photophysical Characterization

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 30, 20 July 2026.
An improved low‐temperature synthesis enables the first comprehensive structural and spectroscopic characterisation of neutral hexacyanotrimethylenecyclopropane (CN6CP). Combined IR/Raman, UV–Vis and ssNMR analyses reveal a deeper understanding of its oxidation‐state‐dependent charge redistribution, σ‐aromaticity of the cyclopropane core, and redox ...
Jan P. Soyka   +8 more
wiley   +1 more source

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng   +3 more
wiley   +1 more source

Exploring oxide quasicrystals in internal space. [PDF]

open access: yesActa Crystallogr A Found Adv
Schenk S   +3 more
europepmc   +1 more source

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