Results 111 to 120 of about 299,752 (288)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Revista Árvore, 2012 O presente trabalho teve por objetivo estudar a evolução tecnológica da produção de madeira para celulose, para tanto, a produção de celulose de fibra curta derivada do eucalipto foi decomposta em efeito área e efeito produtividade. Para isso foi usado o
Kaio Henrique Adame de Carvalho +2 more
doaj
Analisis Pertumbuhan Ekonomi Dan Pengembangan Sektor Potensial Di Kabupaten Jepara (Pendekatan Model Basis Ekonomi) (1995-2010) [PDF]
, 2013 Penelitian ini berjudul “Analisis Pertumbuhan Ekonomi Dan Pengembangan Sektor Potensial Di Kabupaten Jepara (Pendekatan Model Basis Ekonomi (1995-2010)”.
, Ir.Maulidyah IH, M.Si, +1 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Magallania, 2010 El presente trabajo1-2consiste en identificar a la o las actividades económicas que han contribuido al desarrollo de la región de Magallanes, para ello se recurre a dos variables, al Producto Interno Bruto Regionalizado (PIBr) y Empleo por Rama de ...
SERGIO SOZA-AMIGO
doaj
MEASURING ECONOMIC GROWTH IN RURAL COMMUNITIES: THE SHIFT-SHARE APPROACH [PDF]
Community/Rural/Urban Development,
Darling, David L., Gordon, John
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Path Based Shift-Share Analysis -Using Additional Information in Decomposing Regional Economic Changes [PDF]
, 2005 Shift-Share analysis is a well-known methodology frequently used to obtain insights into the determinants of regional growth processes. It can address many issues, such as output growth, employment growth and productivity growth.
Carvajal, Carmen +2 more
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source