Results 91 to 100 of about 60,300 (260)
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
A relative of the shift operator
For a positive number \(\alpha\), define \(E_ \alpha\) by \[ E_ \alpha=\{\lambda\in \mathbb{C}:\;| \lambda-1|+|\lambda +1|\leq \alpha+\alpha^{-1}\}. \] For \(\alpha\neq 1\), \(E_ \alpha\) is a closed elliptic disc. If \(U\) is the unilateral shift on a Hilbert space \(H\), then for any complex number \(\alpha\) define \(U_ \alpha\) by \(U_ \alpha={1 ...
openaire +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Perturbations of the shift operator [PDF]
openaire +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Rapid data traffic growth has led to operator data traffic grow while the income does not grow, network pressure increase, customer experience decline and so on.
Biao He, Mingguang Zhang, Lu Li
doaj +2 more sources
Quantum encryption in phase space with dynamic displacement operators and quantum permutation pad
We propose the Dynamic Displacement Operator (DDO) as part of Quantum Encryption in Phase Space (QEPS-dd), a novel scheme for securing coherent optical communications using Quadrature Amplitude Modulation (QAM).
Randy Kuang
doaj +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source

