Results 91 to 100 of about 60,300 (260)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

A relative of the shift operator

open access: yesLinear Algebra and its Applications, 1992
For a positive number \(\alpha\), define \(E_ \alpha\) by \[ E_ \alpha=\{\lambda\in \mathbb{C}:\;| \lambda-1|+|\lambda +1|\leq \alpha+\alpha^{-1}\}. \] For \(\alpha\neq 1\), \(E_ \alpha\) is a closed elliptic disc. If \(U\) is the unilateral shift on a Hilbert space \(H\), then for any complex number \(\alpha\) define \(U_ \alpha\) by \(U_ \alpha={1 ...
openaire   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Perturbations of the shift operator [PDF]

open access: yesTransactions of the American Mathematical Society, 1965
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Strategy Study to Enhance the Value of Telecom Operators Based on Traffic Management——Empirical Analysis of S Corporation

open access: yesDianxin kexue, 2013
Rapid data traffic growth has led to operator data traffic grow while the income does not grow, network pressure increase, customer experience decline and so on.
Biao He, Mingguang Zhang, Lu Li
doaj   +2 more sources

Quantum encryption in phase space with dynamic displacement operators and quantum permutation pad

open access: yesAcademia Quantum
We propose the Dynamic Displacement Operator (DDO) as part of Quantum Encryption in Phase Space (QEPS-dd), a novel scheme for securing coherent optical communications using Quadrature Amplitude Modulation (QAM).
Randy Kuang
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Home - About - Disclaimer - Privacy