Results 41 to 50 of about 39,068 (265)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

ALGEBRAIC EQUATIONS WITH LINEAR SHIFT OPERATORS ON SEQUENCES [PDF]

open access: yesRomanian Journal of Mathematics and Computer Science, 2016
In this note we recall (see also [8]) the structure of all recurrent sequences which satisfy a fixed recurrence relation, with entries in a perfect field.
SEVER ANGEL POPESCU
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On a Chaotic Weighted Shift zpdp+1/dzp+1 of Order p in Bargmann Space

open access: yesAdvances in Mathematical Physics, 2011
This paper is devoted to the study of the chaotic properties of some specific backward shift unbounded operators Hp=A*pAP+1; p=0,1,… realized as differential operators in Bargmann space, where A and A* are the standard Bose annihilation and creation ...
Abdelkader Intissar
doaj   +1 more source

Mood, sleep patterns and the effect of physical activity on the life quality of brazilian train operators

open access: yesSleep Science, 2012
Objectives: Rotating or night shifts elicit rapid changes in physiology which the body cannot quickly adapt. In addition, alterations in shift work influence social and familial aspects that ultimately impact the quality of life of these ...
Luciana Oliveira e Silva   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

PERBEDAAN WAKTU REAKSI DAN TINGKAT KELELAHAN ANTARA PEKERJA SHIFT PAGI DAN SHIFT MALAM

open access: yesBerkala Kedokteran, 2015
Fatigue is a feeling of weariness or lack of energy that does not decrease when a person rests. The main reason of occupational accidents caused by humans is stress and fatigue.
Olivia Dewi Rianti   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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