Results 51 to 60 of about 624,139 (310)

Competition for FDI and profit shifting: On the effects of subsidies and tax breaks [PDF]

open access: yes, 2013
We investigate competition for FDI within a region when a foreign multinational firm can profitably exploit differences in statutory corporate tax rates by shifting taxable profits to lower-tax jurisdictions.
De Feo, Giuseppe   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Construction and validation of the preliminary version of the pictorial-computer test for executive functions

open access: yesمجله علوم روانشناختی, 2021
Background: Executive functions are a set of high-level cognitive processes that, by influencing low-level processes, enable individuals to direct their thoughts and actions.
mohsen rafikhah   +4 more
doaj  

The impact of the connection of Tharthar Channel to the Euphrates River at Habbaniyah–Fallujah area [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة
Rivers, like any other natural phenomenon, strive to maintain a stable state that is suitable for their environment or region. Any changes in the conditions surrounding the river will make the river out of its stable state.
Ban AL-kubasi, Omar AL-Jarrah
doaj   +1 more source

Executive Function, Language, and the Toddler’s Discovery of Representational Drawing

open access: yesFrontiers in Psychology, 2021
Working memory capacity and executive functions play important roles in the early development of drawing and language, but we lack models that specify the relationships among these representational systems and cognitive functions in toddlers.
Sabrina Panesi   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Dialogic Reading to Empower Executive Functions in Preschoolers

open access: yesChildren, 2021
Among the interventions recently developed to enhance Executive Functions (EFs) in preschoolers, Quincey Quokka’s Quest (QQQ) is an illustrated book proposing EF activities embedded within a shared reading framework (Howard et al., 2017).
Costanza Ruffini   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Shifting Sugars and Shifting Paradigms

open access: yesPLOS Biology, 2015
No organism lives in a constant environment. Based on classical studies in molecular biology, many have viewed microbes as following strict rules for shifting their metabolic activities when prevailing conditions change. For example, students learn that the bacterium Escherichia coli makes proteins for digesting lactose only when lactose is available ...
openaire   +4 more sources

Home - About - Disclaimer - Privacy