Results 151 to 160 of about 3,212,380 (290)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Night shift work and dietary behaviors: a comparative analysis of European night shift and day workers from the SHIFT2HEALTH online survey. [PDF]

Nutr J
Klink U, Feskens EJM, Lucassen DA, Vingerhoeds MH, Haider S, Papantoniou K, Matullat I, Cuparencu C, Aufschnaiter AL, Fuchs-Neuhold B, Höfler C, Wallner M, Binder-Olibrowska KW, Wrzesińska MA, Lammers-van der Holst HM, Santonja I, Scionti K, Schoissengeier V, Wagner KH, Wakolbinger M, Winzer E, Ummels M, Jilani H, SHIFT2HEALTH consortium.   +23 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Detecting gaze shifts of moving observers in dynamic environments. [PDF]

Behav Res Methods
Nejad A, Ghiani A, Cornelissen FW, Brenner E.   +3 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The nature and prevalence of diversification rate shifts across the Tree of Life. [PDF]

Evol Lett
Kopperud BT, Capobianco A, Clarke JT, Palazzesi L, Höhna S.   +4 more
europepmc   +1 more source

Shifting versus shifted cultivators [PDF]

BioScience, 2000
NORMAN MYERS, JEFFERSON FOX, A. TERRY RAMBO, DAO MINH TRUONG, NGHIEM PHUONG TUYEN, LE TRONG CUC, STEPHEN LEISZ   +6 more
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Genetic Diversity Impacts Climate-Induced Species Range Shifts. [PDF]

Ecol Lett
Oliveira BF, Bertrand R, Comte L, Lenoir J, Grenouillet G, Lancaster LT, Murienne J, Diamond S, Scheffers BR, Bandara RMWJ, Lawlor JA, Moore NA, Wolfe BW, Villalobos F, Weiskopf SR, Thompson LM, Pinsky ML, Rolland J.   +17 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source