Results 111 to 120 of about 1,036,191 (291)

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma   +17 more
wiley   +1 more source

Religious Authorities in Contemporary Twelver Shiism

open access: yes, 2004
Face aux pouvoirs politiques en place, les oulémas chiites ont adopté une attitude de réserve, voire de contestation, car ils considèrent que seul l’imam est à même d’exercer l’autorité spirituelle et politique sur la communauté des croyants. À partir du XIe siècle, ils élaborèrent des doctrines leur permettant d’élargir leur autorité religieuse, jusqu’
openaire   +2 more sources

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Problematic Issues of Institutional Development of Islamic Associations in Contemporary Ukraine

open access: yes, 2020
The article analyzes the revival of the Islamic religion which began in Ukraine in the 1990s. The authors point to the problematic issues of the institutional establishment of Islamic associations in contemporary Ukraine.
Ismahilov, Serhii, Sagan, Galyna
core  

Alexander Dugin’s Heideggerianism [PDF]

open access: yes, 2018
This paper argues for the central role of Martin Heidegger’s thought in Alexander Dugin’s political philosophy or political theory. Part one is a broad overview of the place of Heidegger in Dugin’s political theory.
Millerman, Michael
core  

The History of Shiism and the Internet

open access: yesتاریخ اسلام, 2001
تاریخ تشیع در اینترنت: در شماره قبل این فصل نامه, مطلبى با عنوان ((پژوهش ها و منابع مطالعاتى تاریخ اسلام در اینترنت)) ارایه گردید. اینک با انگیزه استمرار جستجو در اینترنت به دنبال یافتن مباحثى در زمینه تاریخ اسلام, مطالبى ارایه مى شود. نگارنده امید دارد که خوانندگان با ارسال دیدگاه و نظرات خود به آدرس پست الکترونیکىac.ir .
openaire   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

Çağdaş İran'da Şiî İmamet Kavramı ve Liderlik: Dinî Modernistlerin Görüşleri

open access: yesTurkish Journal of Shiite Studies, 2019
İmamet On İki İmam Şiiliğinin en önemli esaslarından biridir. Bununla birlikte, son yıllarda anlamı modernistler tarafından büyük ölçüde tartışılmaktadır.
Adel Hashemi-najafabadi   +1 more
doaj  

Propaganda Amaçlı Yazılmış Dini Metinlerin Mezhepler Arası İlişkilere Etkisi: 'Peşaver Geceleri' Örneği

open access: yesTurkish Journal of Shiite Studies
Makalemizin konusu olan Peşaver Geceleri (Şebhâ-yi Pîşâver) isimli kitabın yazarı Seyyid Muhammed Musevî, adı geçen çalışmasını, bir kısım Hindistanlı basın mensubunun huzurunda birkaç Ehl-i Sünnet âlimiyle birlikte yaptığı tartışmaları kayda geçirerek ...
Cemil Hakyemez
doaj   +1 more source

Home - About - Disclaimer - Privacy