Results 61 to 70 of about 413 (218)

Çağdaş Bir Anakronizm Örneği: Ehl-i Hadis Ekolü Temsilcilerinden İhsan İlâhî Zahîr’in Şîa Karşıtlığı Üzerine Bir İnceleme

open access: yesTurkish Journal of Shiite Studies
Ehl-i Hadis ekolünün savunucularından biri olan İhsan İlâhî Zahîr, 20. yüzyıl Hint alt kıtasının siyasi tarihinde birçok önemli olaya şahit olmuş, kırk iki yıllık ömründe gerek yazılarıyla gerekse faaliyetleriyle aktif bir şekilde rol almış önemli bir ...
Gülşen Yağır Ahmetoğlu
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

open access: yesAdvanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu   +11 more
wiley   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

open access: yesAdvanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao   +6 more
wiley   +1 more source

Surviving Persecution: Ismailism and Taqiyyah in the Centuries after the Mongol Invasion [PDF]

open access: yesپژوهش های تاریخی
ʿAṭā-Malik Juwaynī concluded his History of the World Conqueror (Taʾrīkh-i jahān-gushāy) by celebrating the Mongol destruction of the Ismailis at Alamut. For many centuries, historians assumed the community had ceased to exist.
Shafique N. Virani   +2 more
doaj   +1 more source

Role of Sufism in Spreading Shiism at Kermanshah

open access: yesJournal of History Culture and Art Research, 2017
Abstract Researchers, whether Muslim or not, refer to Sufism as limbo between Sunni and Shia beliefs with an emphasis on its weak Sunni and strong Shia ties. History and expand of Shia in Kermanshah support this statement also. Kermanshah is one of the regions that provided a proper social environment for Shia to strengthen its presence due to Sufi ...
Sajjad Dadfar, Ghobad Radeh
openaire   +2 more sources

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

Kadîm Komşumuz İran ve Şii Kültürüne Dair Gezi Notları

open access: yesTurkish Journal of Shiite Studies, 2020
İran gerek mezhebî gerekse siyasî tarih bakımından Ortadoğu’nın önemli merkezlerindendir. Türk dış politikasında da mühim yeri olan bu kadim komşumuzu tanımak bize bölgeyi anlamak adına farklı bakış açısı kazandıracaktır.
Alper Yıldırım
doaj  

Manifestation of Shiite Impressions in Qajar Signet Rings [PDF]

open access: yesنگره, 2012
Islamic signet rings besides decorative aspects have religious and ritual functions. Incised signet rings are very important artifacts in Islamic culture of Iran and wearing them is highly recommended by Shiite clergies.
Akram Mohamadizadeh
doaj  

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