Results 31 to 40 of about 7,326 (212)
Shikonin Derivatives fromLithospermum canescens.
Pharmaceutical Biology, 2005 The phytochemical investigation of Lithospermum canescens (Michx.) Lehm. roots with respect to pigment compounds resulted in the isolation of acetylshikonin and isobutyrylshikonin. Their structures were determined by NMR methods.
A. Pietrosiuk, H. Wiedenfeld
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Effect of Shikonin Against Candida albicans Biofilms [PDF]
Frontiers in Microbiology, 2019 Candidiasis is often associated with the formation of biofilms. Candida albicans biofilms are inherently resistant to many clinical antifungal agents and have increasingly been found to be the sources of C. albicans infections. Novel antifungal agents against C. albicans biofilms are urgently needed.
Yu Yan +4 more
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Antibacterial and cytotoxic activities of naphthoquinone pigments from Onosma visianii Clem [PDF]
, 2017 In this study, the antibacterial and cytotoxic activities of isolated compounds from the roots of Onosma visianii were investigated. By using different chromatographic techniques and appropriate spectroscopic methods, the seven naphthoquinones were ...
Baskic, Dejan D. +8 more
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Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]
, 2001 This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
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Reviews in Analytical Chemistry, 2011 The genus Onosma is represented by 97 species, 4 varieties, 1 hybrid species in the flora of Turkey. Some Onosma species with roots containing naphthoquinones (alkannin, shikonin and alkannin/shikonin derivatives) are known as “Havaciva” in Turkey ...
Ozgen Ufuk +2 more
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Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling [PDF]
, 2010 Background Functional comparative genomic analysis of the cellular immunological effects of different anti-inflammatory phytocompounds is considered as a helpful approach to distinguish the complex and specific bioactivities of candidate ...
Shao-Chih Chiu +5 more
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Anti-tumor effects of shikonin derivatives on human medullary thyroid carcinoma cells
Endocrine Connections, 2017 New treatment options are needed for medullary thyroid carcinoma (MTC), a highly metastasizing neuroendocrine tumor that is resistant to standard radiotherapy and chemotherapy.
Carina Hasenoehrl +6 more
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In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures [PDF]
, 2009 Background Shikonin derivatives have cytotoxic and antitumor effects. This study aims to investigate the antitumor effects of acetylshikonin isolated from a Chinese medicinal herb Arnebia euchroma (Royle) Johnst. Methods The 3-(4,5-dimethylthiazol- 2-yl)-
Wenbi Xiong +4 more
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Biological Effects of Shikonin in Human Gingival Fibroblasts via ERK 1/2 Signaling Pathway
Molecules, 2019 Shikonin, an active ingredient of Lithospermum erythrorhizon, exerts anti-inflammatory and antibacterial effects, and promotes wound healing. We investigated whether shikonin stimulated gingival tissue wound healing in human gingival fibroblasts (hGF ...
Kazutaka Imai +3 more
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Pharmacological Research - Modern Chinese Medicine, 2021 Background: Alteration of polyol pathway is a critical event in serials of disease, including inflammatory bowel disease (IBD). Shikonin, an inhibitor of PKM2, has been reported to exert a wide range of biological and pharmacological properties. However,
Ling Huang +13 more
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