Results 61 to 70 of about 7,326 (212)

Anticancer agent shikonin is an incompetent inducer of cancer drug resistance. [PDF]

PLoS ONE, 2013
PURPOSE: Cancer drug resistance is a major obstacle for the success of chemotherapy. Since most clinical anticancer drugs could induce drug resistance, it is desired to develop candidate drugs that are highly efficacious but incompetent to induce drug ...
Hao Wu, Jiansheng Xie, Qiangrong Pan, Beibei Wang, Danqing Hu, Xun Hu   +5 more
doaj   +1 more source

Targeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi, Jinye Li, Guotian Luo, Jiachen Li, Dahang Yang, Wei Sun, Weichao Sun, Wei You, Lei Yang   +8 more
wiley   +1 more source

インビトロにおけるシコニンおよびデオキシシコニンのリンパ管新生に対する効果 [PDF]

, 2014
富山大学・富医薬博甲第142号・朴俊彦・2014/03/21・★論文非公開 ...
朴 俊彦
core   +1 more source

A Comprehensive Review on the Significance of Antioxidants and Their Influence on Biopolymer Packaging Films: Recent Advances and Challenges

Food Frontiers, Volume 7, Issue 2, March 2026.
Influence of antioxidants‐loaded biopolymer films on food security and extended shelf life. ABSTRACT Autooxidation is a significant cause of quality deterioration in food systems, leading to nutrient loss, off‐flavor formation, textural changes, and overall spoilage.
Sai Kumar Tammina, Rambabu Krishnamoorthy, Arshied Manzoor, Ruchir Priyadarshi, Kandi Sridhar, Fawzi Banat   +5 more
wiley   +1 more source

Denervation does not induce muscle atrophy through oxidative stress [PDF]

, 2017
Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Adamo, Sergio, Bellezza, Ilaria, Fulle, Stefania, Greco, Emanuela, Grottelli, Silvia, Mancinelli, Rosa, Minelli, Alba, Moresi, Viviana, Morozzi, Giulio, Pigna, Eva, Rotini, Alessio   +10 more
core   +3 more sources

Ganoderic Acids Alleviate Neuroinflammation by Targeting Myeloid Differentiation Factor 2 for Ischemic Stroke Therapy

Exploration, Volume 6, Issue 1, February 2026.
Ganoderic acids confer neuroprotection in ischemic stroke by directly targeting MD2, thereby blocking MD2/TLR4 complex formation and downstream MAPK and NF‐κB activation. This suppresses microglia‐driven neuroinflammation and mitigates cerebral ischemic injury.
Ang Ma, Yinhua Zhu, Yi Ying, Shuyuan Wang, Jingsong Zhang, Na Feng, Yazhu Quan, Guangying Shao, Dandan Liu, Shujie Zhang, Xiaoqiang Geng, Hong Zhou, Min Li, Dongmei Lin, Lianfu Wang, Guang Liang, Shaowei Li, Baoxue Yang   +17 more
wiley   +1 more source

Fermentación por adhesión a superficies: una nueva categoría fermentativa [PDF]

, 2003
Se resume el conocimiento básico sobre la fermentación en estado sólido y la formación de biopelículas y se relaciona con los procesos de adhesión celular, cubriendo puntos de vista de ingeniería y de biología molecular.
Gretty K. Villena, Marcel Gutiérrez-Correa   +1 more
core   +3 more sources

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Effects of Saponin and Sophorolipid on the Formation and Stability of Shikonin Lipid Nanoparticles

Shipin gongye ke-ji
Shikonin is a kind of hydrophobic natural pigment with various physiological activities. In order to improve its water solubility, stability and bioavailability, a natural surfactant modified shikonin lipid nanoparticles was developed.
Jie HE, Shengfeng PENG, Junbing ZHANG, Wei LIU   +3 more
doaj   +1 more source

Up-regulation of p21 and TNF-alpha is mediated lycorine-induced death of HL-60 cells [PDF]

, 2010
Background Leukemia is one of the most life-threatening cancers today, and acute promyelogenous leukemia (APL) is a common type of leukemia. Many natural compounds have already been found to exhibit significant anti-tumor effects. Lycorine, a
Jing Liu, Ji-liang Hu, Bi-Wei Shi, Yang He, Wei-Xin Hu   +4 more
core   +2 more sources