Results 81 to 90 of about 7,326 (212)
Dermatologic Therapy, Volume 2026, Issue 1, 2026.Background Although various therapies are available for pressure ulcers, no single treatment has demonstrated superior effectiveness compared to others. Arnebia euchroma exhibits anti‐inflammatory properties that facilitate the healing of surgical wounds and burns. We aimed to evaluate the efficacy of A.
Armaghan Kazeminejad +8 more
wiley +1 more source
Shikonin inhibits intestinal calcium-activated chloride channels and prevents rotaviral diarrhea
Frontiers in Pharmacology, 2016 Secretory diarrhea remains a global health burden and causes major mortality in children. There have been some focuses on antidiarrheal therapies that may reduce fluid losses and intestinal motility in diarrheal diseases.
Yu Jiang, Bo Yu, Hong Yang, Tonghui Ma
doaj +1 more source
Journal of Immunology Research, Volume 2026, Issue 1, 2026.Multiple sclerosis (MS) is a chronic immune‐mediated inflammatory demyelinating disease of the central nervous system (CNS), characterized by multifocal lesions, axonal damage, and progressive neurological dysfunction, imposing a heavy burden on patients and healthcare systems.
Zhiyong Long +6 more
wiley +1 more source
Frontiers in Pharmacology, 2020 Colorectal cancer is a common malignancy occurring in the digestive system, which is the third common cause of cancer mortality in developed countries.
Yang Chen +9 more
doaj +1 more source
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao +5 more
wiley +1 more source
The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer
International Journal of Cancer, Volume 157, Issue 12, Page 2434-2446, 15 December 2025.Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley +1 more source
An in silico approach towards cancer therapy using tumor PKM2 as target [PDF]
, 2014 Cancer is a disease that affects major part of the human population. Though, centuries have been spent upon cancer research many aspects of cancer cell are still undiscovered and thus there has been no effective drug designed that can actually cure ...
Mohanty, V
core
The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. [PDF]
, 2016 Tumor cell resistance to apoptosis, which is triggered by many anti-tumor therapies, remains a major clinical problem. Therefore, development of more efficient therapies is a priority to improve cancer prognosis.
Barras, D. +9 more
core +1 more source
Advanced Science, Volume 12, Issue 48, December 29, 2025.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Shikonin kills glioma cells through necroptosis mediated by RIP-1.
PLoS ONE, 2013 Background and purposeShikonin was reported to induce necroptosis in leukemia cells, but apoptosis in glioma cell lines. Thus, it is needed to clarify whether shikonin could cause necroptosis in glioma cells and investigate its underlying mechanisms ...
Chuanjiang Huang +6 more
doaj +1 more source