Results 71 to 80 of about 74,771 (264)

Efficient Compression Technique for Sparse Sets

, 2017
Recent technological advancements have led to the generation of huge amounts of data over the web, such as text, image, audio and video. Most of this data is high dimensional and sparse, for e.g., the bag-of-words representation used for representing ...
Kulkarni, Raghav, Pratap, Rameshwar, Sohony, Ishan   +2 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD

Experimental Gerontology
Introduction: Diverse pathogens (viral, bacterial, fungal) have been associated with Alzheimer's disease (AD) and related traits in various studies.
Svetlana Ukraintseva, Arseniy P. Yashkin, Igor Akushevich, Konstantin Arbeev, Hongzhe Duan, Galina Gorbunova, Eric Stallard, Anatoliy Yashin   +7 more
doaj   +1 more source

Building integration photovoltaic module with reference to Ghana: using triple junction amorphous silicon [PDF]

, 2010
This paper assesses the potential for using building integrated photovoltaic (BIPV) roof shingles made from triple-junction amorphous silicon (3a-Si) for electrification and as a roofing material in tropical countries, such as Accra, Ghana.
Essah, Emmanuel Adu
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

〔報告〕こけら屋根に用いた銅板の防腐効果について [PDF]

, 2012
The preservative effect of copper plates against the decay of wooden shingles used for a traditional style roof was studied. Copper (Cu)plates sheeted under wooden shingles are expected to be a source of Cu elements when the shingles and plates are ...
木川 りか, 藤井 義久, 藤原 裕子   +2 more
core   +1 more source

A Comparison of Blocking Methods for Record Linkage

, 2014
Record linkage seeks to merge databases and to remove duplicates when unique identifiers are not available. Most approaches use blocking techniques to reduce the computational complexity associated with record linkage.
A. Goldenberg, D. Vatsalan, H. Liang, L. Paulevé, M. Kuzu, P. Christen, P. Christen, P. Christen, R. Hall, S. Fortunato, T. Herzog   +10 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Shingles Case Study: Too late to treat?

South African Family Practice, 1993
No abstract available.
K. Russell
doaj   +1 more source