Results 101 to 110 of about 453 (130)
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Photosynthetic Production of Sunscreen Shinorine Using an Engineered Cyanobacterium
ACS Synthetic Biology, 2018Mycosporine-like amino acids (MAAs) are secondary metabolites of a variety of marine organisms including cyanobacteria and macroalgae. These compounds have strong ultraviolet (UV) absorption maxima between 310 and 362 nm and are biological sunscreens for counteracting the damaging effects of UV radiation in nature.
Guang Yang +2 more
exaly +3 more sources
Aquatic Toxicology, 2020
Hexavalent chromium, a heavy metal toxicant, abundantly found in the environment showed hepatotoxic potential in zebrafish liver and instigated the Nrf2-Keap1-ARE pathway as a cellular stress response as reported in our previous studies. In the present study we have evaluated the ameliorating effect of shinorine, a mycosporine like amino acid (MAAs ...
Ansuman Chattopadhyay +2 more
exaly +3 more sources
Hexavalent chromium, a heavy metal toxicant, abundantly found in the environment showed hepatotoxic potential in zebrafish liver and instigated the Nrf2-Keap1-ARE pathway as a cellular stress response as reported in our previous studies. In the present study we have evaluated the ameliorating effect of shinorine, a mycosporine like amino acid (MAAs ...
Ansuman Chattopadhyay +2 more
exaly +3 more sources
Metabolic Engineering, 2023
Mycosporine-like amino acids (MAAs) are promising natural sunscreens mainly produced in marine organisms. Until now, metabolic engineering efforts to produce MAAs in heterologous hosts have mainly focused on shinorine production, and the low production levels are still not suitable for industrial applications.
Ji-Sook Hahn
exaly +3 more sources
Mycosporine-like amino acids (MAAs) are promising natural sunscreens mainly produced in marine organisms. Until now, metabolic engineering efforts to produce MAAs in heterologous hosts have mainly focused on shinorine production, and the low production levels are still not suitable for industrial applications.
Ji-Sook Hahn
exaly +3 more sources
Journal of Agricultural and Food Chemistry, 2022
Mycosporine-like amino acids (MAAs) have been used in cosmetics and pharmaceuticals. The purpose of this work was to develop yeast strains for sustainable and economical production of MAAs, especially shinorine. First, genes involved in MAA biosynthetic pathway from Actinosynnema mirum were introduced into Saccharomyces cerevisiae for heterologous ...
So-Rim Kim +8 more
openaire +2 more sources
Mycosporine-like amino acids (MAAs) have been used in cosmetics and pharmaceuticals. The purpose of this work was to develop yeast strains for sustainable and economical production of MAAs, especially shinorine. First, genes involved in MAA biosynthetic pathway from Actinosynnema mirum were introduced into Saccharomyces cerevisiae for heterologous ...
So-Rim Kim +8 more
openaire +2 more sources
Biochimie, 2018 Mycosporine-like amino acids (MAAs) are UVR-absorbing metabolites typically produced by cyanobacteria and marine algae, but their properties are not limited to direct sun screening protection. Herein, we examine the antioxidant activities of porphyra-334 and shinorine and demonstrate that these MAAs are prospective activators of the cytoprotective ...
Paul Long +2 more
exaly +6 more sources
Photochemistry and Photophysics of Shinorine Dimethyl Ester
Photochemistry and Photobiology, 2018AbstractThe photostability and photophysical properties of the dimethyl ester of the mycosporine‐like amino acid shinorine have been experimentally evaluated in aqueous solution and in the presence of direct micelles prepared with a cationic or an anionic detergent, respectively.
Sonia Bertolotti +2 more
exaly +4 more sources
Photochemistry and Photobiology, 2004
ABSTRACTTo determine the action spectrum for photoinduction of the ultraviolet (UV)‐absorbing mycosporine‐like amino acid shinorine, specimens of the marine red alga Chondrus crispus were irradiated with monochromatic light of various wavelengths using the Okazaki large spectrograph at the National Institute for Basic Biology, Okazaki, Japan.
Masakatsu Watanabe, Christian Wiencke
exaly +5 more sources
ABSTRACTTo determine the action spectrum for photoinduction of the ultraviolet (UV)‐absorbing mycosporine‐like amino acid shinorine, specimens of the marine red alga Chondrus crispus were irradiated with monochromatic light of various wavelengths using the Okazaki large spectrograph at the National Institute for Basic Biology, Okazaki, Japan.
Masakatsu Watanabe, Christian Wiencke
exaly +5 more sources
ACS Synthetic Biology, 2018
Shinorine, a mycosporine-like amino acid (MAA), is a small molecule sunscreen produced in some bacteria. In this study, by introducing shinorine biosynthetic genes from cyanobacteria Nostoc punctiform into Saccharomyces cerevisiae, we successfully constructed yeast strains capable of producing shinorine. Sedoheptulose 7-phosphate (S7P), an intermediate
Seong-Hee Park +3 more
openaire +2 more sources
Shinorine, a mycosporine-like amino acid (MAA), is a small molecule sunscreen produced in some bacteria. In this study, by introducing shinorine biosynthetic genes from cyanobacteria Nostoc punctiform into Saccharomyces cerevisiae, we successfully constructed yeast strains capable of producing shinorine. Sedoheptulose 7-phosphate (S7P), an intermediate
Seong-Hee Park +3 more
openaire +2 more sources
Photochemical & Photobiological Sciences, 2004
In vitro studies on the structurally related mycosporine-like amino acids (MAAs) porphyra-334 and shinorine in aqueous solutions were carried out aiming at their full photochemical and photophysical characterization and expanding the evidence on the assigned UV-photoprotective role of the molecules in vivo. The experiments on shinorine confirmed a high
Federico R, Conde +2 more
openaire +2 more sources
In vitro studies on the structurally related mycosporine-like amino acids (MAAs) porphyra-334 and shinorine in aqueous solutions were carried out aiming at their full photochemical and photophysical characterization and expanding the evidence on the assigned UV-photoprotective role of the molecules in vivo. The experiments on shinorine confirmed a high
Federico R, Conde +2 more
openaire +2 more sources
Acta Physiologiae Plantarum, 2013
Cyanobacteria are known to biosynthesize mycosporine-like amino acids (MAAs) as photoprotective compounds against ultraviolet radiation. Anabaena sp., isolated from the hot springs of Rajgir, India, produces a single MAA shinorine (retention time = 2.2 min and absorption maximum at 334 nm) as purified by high-performance liquid chromatography.
Rajeshwar Sinha +2 more
exaly +2 more sources
Cyanobacteria are known to biosynthesize mycosporine-like amino acids (MAAs) as photoprotective compounds against ultraviolet radiation. Anabaena sp., isolated from the hot springs of Rajgir, India, produces a single MAA shinorine (retention time = 2.2 min and absorption maximum at 334 nm) as purified by high-performance liquid chromatography.
Rajeshwar Sinha +2 more
exaly +2 more sources