Results 31 to 40 of about 121,011 (314)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Inventory Management for Irregular Shipment of Goods in Distribution Centre

open access: yesIOP Conference Series: Materials Science and Engineering, 2016
The shipping amount of commodity goods (Foods, confectionery, dairy products, such as public cosmetic pharmaceutical products) changes irregularly at the distribution center dealing with the general consumer goods. Because the shipment time and the amount of the shipment are irregular, the demand forecast becomes very difficult. For this, the inventory
Hitoshi Takeda   +2 more
openaire   +1 more source

An Optimization Model for Single-Warehouse Multi-Agents Distribution Network Problems under Varying of Transportation Facilities: A Case Study [PDF]

open access: yes, 2008
The transportation cost of goods is the highest day-to-day operational cost associated with the food industry sector. A company may be able to reduce logistics cost and simultaneously improve service level by optimizing
Fauziati, Alfin Nuriya   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Improving a Firm's Performance within a Strategic Shipping Alliance

open access: yesAsian Journal of Shipping and Logistics, 2019
Shipping companies have proactively participated in various strategic alliances within the industry to improve their competitive advantage. Previous studies have addressed how shipping companies gain benefits from strategic alliances.
Eon-Seong Lee
doaj   +1 more source

Impact of maritime logistics on archipelagic economic development in eastern Indonesia

open access: yesAsian Journal of Shipping and Logistics, 2021
The efficiency of logistics is a determinant in developing trade cooperation between regions. Many areas in the eastern part of Indonesia have a flawed logistics system that results in a low level of competitiveness.
Chairullah Amin   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE PRICE DIFFERENTIATION STRATEGY FOR MULTI-SEGMENT MARKET: CASE STUDY IN AN INTERNATIONAL SHIPPING COMPANY [PDF]

open access: yes, 2012
The global market gives opportunities to the shipping company to develop its business, such as the larger market, the addition of new routes, the broader port of destinations, and the development of services.
Rinawiyanti, Esti Dwi
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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