Results 91 to 100 of about 13,878 (248)

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Understanding Pathways to Recidivism Among Children in Türkiye: Insights From Social Workers on Needs, Neglect and Systemic Gaps

Child &Family Social Work, EarlyView.
ABSTRACT Türkiye has experienced a notable increase in juvenile delinquency in recent years, raising serious concerns about child welfare and juvenile justice systems. This qualitative study examines the socio‐economic and structural dimensions of recidivism based on the field experiences of 20 social workers working with children drawn into crime ...
Hüseyin Batman, Aykut Can Demirel, Murat Derin, Metin Gani Tapan   +3 more
wiley   +1 more source

Smartphone Prospects in Bridge Structural Health Monitoring, a Literature Review

Sensors
Bridges are critical components of transportation networks, and their conditions have effects on societal well-being, the economy, and the environment. Automation needs in inspections and maintenance have made structural health monitoring (SHM) systems a
Ekin Ozer, Rolands Kromanis
doaj   +1 more source

Interactive Groupwise Comparison for Reinforcement Learning from Human Feedback

Computer Graphics Forum, EarlyView.
The standard RLHF uses pairwise comparisons and therefore requires a large number of comparisons leading to a high workload. The comparison pairs are suggested by the system and cannot be chosen by the user. Our RLHF approach provides more agency to the user and demands less work: we leverage the user's visual abilities to effectively explore the ...
Jan Kompatscher, Danqing Shi, Giovanna Varni, Tino Weinkauf, Antti Oulasvirta   +4 more
wiley   +1 more source

Establishing Shape Correspondences: A Survey

Computer Graphics Forum, EarlyView.
Abstract Shape correspondence between surfaces in 3D is a central problem in geometry processing, concerned with establishing meaningful relations between surfaces. While all correspondence problems share this goal, specific formulations can differ significantly: Downstream applications require certain properties that correspondences must satisfy ...
A. Heuschling, H. Meinhold, L. Kobbelt
wiley   +1 more source

SharpEdge: Edge Feature Surface Reconstruction From Space Curves

Computer Graphics Forum, EarlyView.
SharpEdge reconstructs surfaces with sharp features from sparse 3D curve networks. By estimating dual normals along curves, our method preserves ridges and corners while producing high‐quality meshes. Abstract Reconstructing high‐quality surfaces from sparse 3D space curves remains challenging, particularly when sharp feature edges are involved ...
X. Yu, A. Sheffer, N. Carr, Y. Gingold
wiley   +1 more source

Prevalence of traded bird species in key biodiversity areas

Conservation Biology, EarlyView.
Abstract The use and trade of biodiversity involve tens of thousands of species that are exploited at a range of scales, intensities, and degrees of sustainability. As a result, some are highly threatened. Key biodiversity areas (KBAs) are sites of significance for the persistence of biodiversity identified nationally based on standardized criteria ...
Oscar Morton, Tom Lansley, Stuart H. M. Butchart, Graeme M. Buchanan, David P. Edwards   +4 more
wiley   +1 more source

Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and other non‐communicable diseases. The role and contribution of various ART regimens to adverse metabolic outcomes are not fully understood.
Melani Ratih Mahanani, Myo Chit, Sophie Mohr, Elisenda Cama i Gibernau, Svetlana Hetjens, Volker Winkler, Hans‐Michael Steffen, Florian Neuhann   +7 more
wiley   +1 more source

Differences in HIV testing may determine the first pillar of the HIV care continuum in a cross‐border setting

HIV Medicine, EarlyView.
Abstract Introduction In border regions like the EuRegio Meuse‐Rhine (EMR), mobility does not stop at the border. HIV risk may therefore not only be determined by within‐country factors but also by between‐country differences. We explored between‐country differences in HIV indicators in the EMR using two complementary data‐driven approaches.
Hanne M. L. Zimmermann, Sarah E. Stutterheim, Dominique van Beckhoven, Wim vanden Berghe, Jessika Deblonde, Sandrine Detandt, Ulrich Marcus, Ben Serrien, Ard van Sighem, Kai J. Jonas   +9 more
wiley   +1 more source

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, EarlyView.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source