Results 161 to 170 of about 91,505 (268)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

e²FAST: Integrating Inferior Vena Cava Ultrasound Into the Extended Focused Assessment With Sonography for Trauma as a Rapid Diagnostic Tool of Hemorrhagic Shock in Trauma Patients. [PDF]

Cureus
Alsalmi F, Nemeth J, Alshaaban M.
europepmc   +1 more source

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

British Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich, Paul Schilf, Sripriya Murthy, Sina Gonther, Mareike Neumann, Christoph M. Hammers, Jasper N. Pruessmann, Christian D. Sadik   +7 more
wiley   +1 more source

Analysis of the effect of arterial embolization combined with external fixation in the treatment of unstable pelvic fracture with hemorrhagic shock. [PDF]

Sci Rep
Shao J, Xie C, Yao W, Huang G, Chu J.
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

Cell Proliferation, EarlyView.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao, Long Jin, Jun Zhong, Qianying Huang, Zhongwei Bao, Shaolong Zhou, Chaohua Wang, Huanhuan Li, Xiaowei Yuan, Zhen Wang, Ning Du, Jingxuan Yu, Huanran Chen, Xuyang Zhang, Hongfei Ge, Jianheng Wu   +15 more
wiley   +1 more source

Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman. [PDF]

Front Med (Lausanne)
Chen J, Zhao Z, Huang K, Zhang L, Cui J, Bai Z, Yu A, Li J, Zhang Z, Chen K.   +9 more
europepmc   +1 more source

Prevalence and Diagnostic Challenge of Hemophagocytic Lymphohistiocytosis Syndrome in Critically Ill Patients

European Journal of Haematology, EarlyView.
ABSTRACT Background Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is a severe condition with a challenging diagnosis in the intensive care unit (ICU), for which current recommendations rely on fulfilling five of eight HLH‐2004 criteria.
Claire Queffeulou, Mathieu Bellal, Suzanne Goursaud, Sylvain Chantepie, Damien du Cheyron   +4 more
wiley   +1 more source

[Hemorrhagic shock].

Folha medica, 1966
  +7 more sources

Shock-Related Thyroid Changes: A Rare Presentation in a Young Patient With Hemorrhagic Shock Secondary to a Road Traffic Accident. [PDF]

Cureus
Thakur A, Bhatia P, Sharma A, Mavuduru S, Panda A.   +4 more
europepmc   +1 more source