Results 191 to 200 of about 1,277,100 (325)

CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin, Noa G. Holtzman, Challice L. Bonifant   +2 more
wiley   +1 more source

Peptidomic Analysis of Rat Plasma: Proteolysis in Hemorrhagic Shock

Shock, 2016
F. Aletti, E. Maffioli, A. Negri, M. Santamaria, F. DeLano, E. Kistler, G. Schmid-Schönbein, G. Tedeschi   +7 more
semanticscholar   +1 more source

Blockade of Endothelial Growth Factor, Angiopoietin-2, Reduces Indices of Ards and Mortality in Mice Resulting from the Dual-Insults of Hemorrhagic Shock and Sepsis

Shock, 2016
Joanne L. Lomas-Neira, Daithi S. Heffernan, A. Ayala, S. Monaghan   +3 more
semanticscholar   +1 more source

Delayed perinephric hematoma following ESWL in an anticoagulated patient: A case report. [PDF]

Int J Surg Case Rep
Eid A, Hassouneh A, Bishawi S, Milhem A, Dibas J, Baradia S.   +5 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Hemorrhagic shock after dental extractions in a patient with anticoagulant and antiplatelet therapy: a case report. [PDF]

Int J Surg Case Rep
Pouplin A, Pham Kormann D, Dolivet G, Phulpin B.   +3 more
europepmc   +1 more source

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

Cell Proliferation, EarlyView.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng, Xiaowen Wang, Haoqi Chen, Kaiming He, Xijing Yan, Yuan Zhang, Yang Yang, Peng Zhang, Wenfeng Zhu, Shuguang Zhu, Hua Li   +10 more
wiley   +1 more source

Optimal Fluid Therapy for Traumatic Hemorrhagic Shock.

Critical care clinics, 2017
Ronald Chang, J. Holcomb
semanticscholar   +1 more source

A Case of Hemorrhagic Shock for a Ruptured Splenic Aneurysm Treated With REBOA-Assisted Surgery. [PDF]

Case Rep Surg
D'Alterio C, Carruezzo C, Raso A, Di Martino A, Santoro R, Giannotti D.   +5 more
europepmc   +1 more source

Partial Resuscitative Endovascular Balloon Occlusion of the Aorta in Swine Model of Hemorrhagic Shock.

Journal of the American College of Surgeons, 2016
Rachel M. Russo, L. Neff, C. Lamb, Jeremy W. Cannon, Joseph M. Galante, Nathan F. Clement, J. K. Grayson, T. Williams   +7 more
semanticscholar   +1 more source