Results 41 to 50 of about 552,748 (296)

Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?

World Journal of Emergency Surgery, 2019
Background Hemorrhagic shock can lead to intestinal damage with subsequent hyperinflammation and multiple organ dysfunction syndrome (MODS). The intestinal fatty acid-binding protein (I-FABP) is solely expressed in the intestine and is released ...
Maika Voth, Thomas Lustenberger, Borna Relja, Ingo Marzi   +3 more
doaj   +1 more source

Class of hemorrhagic shock is associated with progressive diastolic coronary flow reversal and diminished left ventricular function

Frontiers in Physiology, 2022
Introduction: The relationship between coronary artery flow and left ventricular (LV) function during hemorrhagic shock remains unknown. The aim of this study was to quantify coronary artery flow directionality alongside left ventricular function through
Noha N. Elansary, Noha N. Elansary, David P. Stonko, Rebecca N. Treffalls, Hossam Abdou, Marta J. Madurska, Jonathan J. Morrison   +6 more
doaj   +1 more source

Minocycline decreases liver injury after hemorrhagic shock and resuscitation in mice [PDF]

, 2012
Patients that survive hemorrhage and resuscitation (H/R) may develop a systemic inflammatory response syndrome (SIRS) that leads to dysfunction of vital organs (multiple organ dysfunction syndrome, MODS).
Zhong, Zhi, Lehnert, Mark, Marzi, Ingo, Kholmukhamedov, Andaleb, Ramshesh, Venkat K., Maldonado, Eduardo N., Lemasters, John J., Czerny, Christoph, Theruvath, Tom Prakash   +8 more
core   +1 more source

Mineralocorticoid Deficiency in Hemorrhagic Shock [PDF]

Journal of Surgical Research, 2012
In the critically ill, mineralocorticoid deficiency (MD) is associated with greater disease severity, the development of acute renal insufficiency, and increased mortality. We hypothesized that severely injured trauma patients presenting with hemorrhagic shock would demonstrate a high degree of MD.
Nikolai S, Tolstoy, Majid, Aized, Morgan P, McMonagle, Daniel N, Holena, Jose L, Pascual, Seema S, Sonnad, Carrie A, Sims   +6 more
openaire   +2 more sources

An Ovine Model of Hemorrhagic Shock and Resuscitation, to Assess Recovery of Tissue Oxygen Delivery and Oxygen Debt, and Inform Patient Blood Management. [PDF]

, 2022
BACKGROUND: Aggressive fluid or blood component transfusion for severe hemorrhagic shock may restore macrocirculatory parameters, but not always improve microcirculatory perfusion and tissue oxygen delivery.
Ainola, C, Simonova, G, Palmieri, C, Jung, J-S, Wildi, K, Irving, DO, Temple, FT, Li Bassi, G, Chiaretti, S, Tung, J-P, Shuker, T, Dyer, WB, Suen, JY, Rozencwajg, S, Shander, A, Fraser, JF, Colombo, SM   +16 more
core   +1 more source

Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock.

, 2015
Hemorrhagic shock may contribute to acute kidney injury (AKI) by profoundly altering renal mitochondrial function. Resveratrol (RSV), a naturally occurring sirtuin 1 (SIRT1) activator, has been shown to promote mitochondrial function and reduce oxidative
Becker, Lance B, Becker, Lance B., Baur, Joseph A., Karamercan, Mehmet Akif, Baur, Joseph A, Sims, Carrie A, Ye, Lan, Bhatti, Tricia, Sims, Carrie A., Guan, Yuxia, Wang, Hao   +10 more
core   +2 more sources

Hydrogen Molecule Delivery System to Ischemic Intestine Using Resuscitative Endovascular Balloon Occlusion of Aorta in Hemorrhagic Shock—A Proof-of-Concept Study

Biomedicines
Background: The use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for hemorrhagic shock in the torso has become increasingly common as a bridge to definitive hemostasis.
Takahiro Yamanaka, Tadashi Matsuoka, Koichiro Homma, Tomoyoshi Tamura, Sayuri Suzuki, Shohei Suzuki, Daiki Kaito, Jo Yoshizawa, Keitaro Yajima, Soichiro Ono, Katsuya Maeshima, Eiji Kobayashi, Motoaki Sano, Junichi Sasaki   +13 more
doaj   +1 more source

Preperitoneal pelvic packing as a salvage operation for postoperative retroperitoneal bleeding with hemodynamic instability after the Kocher-Langenbeck approach to the acetabulum: a case report [PDF]

Journal of Trauma and Injury
Pelvic fractures result from high-energy trauma, and when accompanied by hemorrhagic shock, the mortality rate increases to 40%. Pelvic fractures are anatomically categorized as pelvic ring disruptions and acetabular fractures, each requiring different ...
Doo-Hun Kim, Maru Kim, Dae-Sang Lee, Tae Hwa Hong, Hangjoo Cho   +4 more
doaj   +1 more source

SHOCK, HEMORRHAGE AND SEPTCEMIA. [PDF]

JAMA: The Journal of the American Medical Association, 1899
In tabulating the symptoms of shock and hemorrhage, we usually note the following : An expressionless countenance, pallor, with corresponding coldness of face and mucous membrane, and clammy skin, often slight or profuse sweats, chilly sensations, irregular heart action, with weak, irregular, thready, often imperceptible pulse, and irregular sighing ...
openaire   +2 more sources

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source