Results 261 to 270 of about 953,820 (321)

Dynamic Response and Energy Absorption of Lattice Sandwich Composite Structures Under Underwater Explosive Load. [PDF]

Materials (Basel)
Zhang X, Sun S, Kang X, Huang Z, Li Y.
europepmc   +1 more source

Polyplex Nanomicelle‐Mediated Pgc‐1α4 mRNA Delivery Via Hydrodynamic Limb Vein Injection Enhances Damage Resistance in Duchenne Muscular Dystrophy Mice

Advanced Science, EarlyView.
This study presents a novel approach for treating Duchenne muscular dystrophy using mRNA encoding PGC‐1α4. Nanomicelle‐delivered Pgc‐1α4 mRNA enhances muscle damage resistance and mitochondrial activity in dystrophic muscles. This study demonstrates the potential of mRNA therapy for neuromuscular diseases like Duchenne muscular dystrophy and highlights
Xuan Du, Hideyuki Nakanishi, Takashi Yamada, Yooksil Sin, Katsura Minegishi, Norio Motohashi, Yoshitsugu Aoki, Keiji Itaka   +7 more
wiley   +1 more source

Study on the diagnostic role of exosome-derived miRNAs in postoperative septic shock and non-septic shock patients. [PDF]

Crit Care
García-Concejo A, Sánchez-Quirós B, Gómez-Sánchez E, Sánchez-de Prada L, Tamayo-Velasco Á, Tovar-Doncel MS, Lorenzo M, Gómez-Pesquera E, Poves-Álvarez R, Bernardo D, Martín-Fernández M, Gonzalo-Benito H, Moreno-Portales P, Prieto-Utrera R, Bardají-Carrillo M, López-Herrero R, Fernández Arranz M, Calaveras-Fernández R, Tomillo-Cebrián F, Aydillo T, Jiménez-Sousa MÁ, Fernández-Rodríguez A, Resino S, Heredia-Rodríguez M, Martínez-Paz P, Tamayo E.   +25 more
europepmc   +1 more source

Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury

Advanced Science, EarlyView.
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang, Zeli Xiang, Pengfei Yang, Ling Zhang, Jun Deng, Xiaohui Liao   +5 more
wiley   +1 more source

Value of lung ultrasound scores in assessing extravascular lung water in septic shock patients. [PDF]

Sci Rep
Zhang X, Li Z.
europepmc   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

Advanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang   +11 more
wiley   +1 more source

Numerical Investigation of Effect of Nozzle Upper Divergent Angle on Asymmetric Rectangular Section Ejector. [PDF]

Entropy (Basel)
Lu M, Dong J, Feng C, Song S, Zhang M, Wang R.   +5 more
europepmc   +1 more source

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

Advanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, Jie Zhang, Shengxi Wu   +11 more
wiley   +1 more source

Risk, rate or rhythm control for new onset supraventricular arrhythmia during septic shock: protocol for the CAFS multicentre, parallel-group, open-label trial. [PDF]

BMJ Open
Labbé V, Desnos C, Preau S, Doyen D, Contou D, Bagate F, Souweine B, Pey V, Bertrand PM, Müller G, Boissier F, Asfar P, Bonnet N, Joffre J, Sy O, Dres M, Annoni F, Monnet X, Carreira S, Vivier E, Serck N, Wiart A, Voicu S, Heming N, Le Breton C, Chevrel G, Chemouni F, Piagnerelli M, Haentjens L, Fartoukh M, Taccone F, Durand D, Monthieux G, Berard L, Rousseau A, Mekontso Dessap A.   +35 more
europepmc   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source