Results 91 to 100 of about 97,848 (354)

Circulatory Disease in the NHS: Measuring Trends in Hospital Costs and Output [PDF]

Following the publication of the Atkinson Review of the measurement of government outputs in the National Accounts, there has been great interest in measuring the productivity growth of the National Health Service. Such macro measures of productivity are
Adriana Castelli, Peter C Smith
core  

Scandinavian SSAI clinical practice guideline on choice of inotropic agent for patients with acute circulatory failure [PDF]

, 2018
BackgroundAdult critically ill patients often suffer from acute circulatory failure and those with low cardiac output may be treated with inotropic agents.
Adamopoulos, Alhashemi, Alvarez, Alvarez, Arrigo, Bergh, Brouwers, Cholley, Coletta, De Backer, De Backer, Duygu, Feneck, Follath, Gamper, Garcia-Gonzalez, Gordon, Guyatt, Guyatt, Guyatt, Guyatt, Hajjej, Hultcrantz, Iyisoy, Jammer, Jentzer, Karlsberg, Koster, Laine, Landoni, Landoni, Levin, Levin, Mahmoud, Mebazaa, Mehta, Memis, Moller, Morelli, Perner, Perner, Qaseem, Rochwerg, Samimi-Fard, Savovic, Vaitsis, Vincent, Wetterslev, Wilkman, Yilmaz, Yontar   +50 more
core   +3 more sources

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

THE REACTIVITY OF THE BLOOD: In Relation to Cardiac Breathlessness, Surgical Shock, and Allied Conditions of the Nervous and Circulatory Systems [PDF]

, 1918
B. Moore
openalex   +1 more source

Biomimetic Thermal Safety Strategies in Batteries for Electric Vehicles: from Biological Principles to Engineering Approaches

Advanced Science, EarlyView.
Biological principles derived from natural structures and functions inspire novel biomimetic strategies for battery thermal safety. This review summarizes applications of biomimetic concepts in preventing thermal runaway, highlighting design strategies that enhance thermal safety protection.
Weifeng Li, Zhongchun Wang, Yao Xue, Zhenhai Gao, Huanli Sun, Ximin Zhai, Deping Wang, Yupeng Chen   +7 more
wiley   +1 more source

Circulatory collapse requiring mechanical circulatory support in a child with autoimmune adrenal insufficiency: a case report

BMC Pediatrics
Background We report a rare case of new onset autoimmune adrenal insufficiency in childhood, presenting with severe shock requiring mechanical circulatory support.
Yahia Hejazi, Ken Tegtmeyer, Meghan Chlebowski, Katja M. Gist   +3 more
doaj   +1 more source

Outcomes of following transcatheter and surgical interventions in patients with acute valvular dysfunction with cardiogenic shockCentral MessagePerspective

JTCVS Open
Objectives: Although surgery remains the gold standard treatment for acute valvular dysfunction complicated by cardiogenic shock, transcatheter management has emerged as an alternative.
Yu Hohri, MD, PhD, Erfan Faridmoayer, MD, Yanling Zhao, MS, MPH, Paul Kurlansky, MD, Krushang Patel, MD, Morgan Moroi, MD, Christine Yang, BS, Giovanni Ferrari, PhD, Isaac George, MD, Hiroo Takayama, MD, PhD, Koji Takeda, MD, PhD   +10 more
doaj   +1 more source

Adrenal Crisis [PDF]

, 2019
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik, Rushworth, R Louise, Torpy, David J   +2 more
core   +1 more source

Circulatory Consequences of Changes in Cardiac Rhythm Produced in Patients by Transthoracic Direct-Current Shock* [PDF]

, 1964
John S. Graettinger, Richard A. Carleton, Joseph J. Muenster   +2 more
openalex   +1 more source