Results 111 to 120 of about 1,009,891 (343)

Clinical Practice Patterns in Temporary Mechanical Circulatory Support for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry.

Circulation: Heart Failure, 2019
BACKGROUND Temporary mechanical circulatory support (MCS) devices provide hemodynamic assistance for shock refractory to pharmacological treatment. Most registries have focused on single devices or specific etiologies of shock, limiting data regarding ...
D. Berg, Christopher F. Barnett, B. Kenigsberg, A. Papolos, Carlos L. Alviar, Vivian M. Baird-Zars, G. Barsness, E. Bohula, J. Brennan, James A. Burke, Anthony P. Carnicelli, S. Chaudhry, Paul C. Cremer, Lori B. Daniels, A. DeFilippis, D. Gerber, Christopher B. Granger, S. Hollenberg, James M. Horowitz, J. Gladden, Jason N. Katz, Ellen C. Keeley, N. Keller, M. Kontos, P. Lawler, V. Menon, Thomas S. Metkus, P. E. Miller, J. Nativi-Nicolau, L. K. Newby, Jeong-Gun Park, Nicholas Phreaner, Robert O. Roswell, Steven P. Schulman, S. Sinha, R. Snell, Michael A Solomon, Jeffrey J. Teuteberg, W. Tymchak, Sean van Diepen, D. Morrow   +40 more
semanticscholar   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

A method of producing cardiac arrest in the dog. [PDF]

, 1953
Thesis (M.A.)--Boston ...
Ryan, Martin Lester
core   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Mechanical circulatory support in patients in cardiogenenic shock

Сучасні медичні технології
Cardiogenic shock in acute myocardial infarction is a life-threatening syndrome characterized by systemic hypoperfusion that can rapidly progress to multiple organ failure and death.
V. H. Tanskyi
doaj   +1 more source

Duration of hemodynamic effects of crystalloids in patients with circulatory shock after initial resuscitation [PDF]

, 2014
Background: in the later stages of circulatory shock, monitoring should help to avoid fluid overload. in this setting, volume expansion is ideally indicated only for patients in whom the cardiac index (CI) is expected to increase.
Azevedo, Luciano Cesar Pontes de, Bafi, Antonio Tonete, Freitas, Flavio Geraldo Rezende, Ladeira, Renata Teixeira, Machado, Flavia Ribeiro, Nunes, Thieme Souza Oliveira   +5 more
core   +3 more sources

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Dynamic Fibrous Hydrogels for Stem Cell Homing and In Situ Bone Regeneration

Advanced Science, EarlyView.
A dynamic fibrous hydrogel (DFH) is developed by covalent crosslinking of gelatin with tea‐derived trichomes, which integrates the structural and compositional fidelity of native extracellular matrix with photothermal and oxidative responsiveness, introducing a novel “stem cell recruits stem cell” strategy that orchestrates co‐homing of endogenous and ...
Jianmei Chen, Meiling Su, Xinyu Wu, Hongyu Wu, Haotian Wu, Pinghu Zhang, Xueying An, Zongguang Liu   +7 more
wiley   +1 more source

Impellent impeller—Switching intra‐aortic balloon pump to IMPELLA‐CP after ST‐segment elevation myocardial infarction and refractory cardiogenic shock

Clinical Case Reports, 2019
Cardiogenic shock is a dreadful complication of myocardial infarction. Despite widespread use and availability, intra‐aortic balloon pump (IABP) does not reduce mortality nor improves outcomes.
Marco Contarini, Francesco Costa, Maria Victoria Garcia Ruiz, Renato F. M. Scalise, Giovanni De Velli, Paola Murè, Paolo Mazzone, Giorgio Sacchetta, Giuseppe Andò   +8 more
doaj   +1 more source

In vitro effect of canine hyperimmune sera on TNFa activity [PDF]

, 2006
[Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5].
Kotiw, Michael, Reeve-Johnson, Lloyd, Shiels, I. A., Wilson, R. P.   +3 more
core   +2 more sources