Results 141 to 150 of about 97,859 (297)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry. [PDF]

JACC Adv
Li S, Mahr C, Kataria R, Ton VK, Zweck E, Kanwar MK, Sinha SS, Garan AR, Hernandez-Montfort J, Abraham J, Burkhoff D, Yeh RW, Møller JE, Thiele H, Kapur NK, CSWG Academic Research Consortium.   +15 more
europepmc   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Percutaneous closure of ventricular septal rupture after myocardial infarction: a case report of competing timelines in multifactorial shock. [PDF]

Eur Heart J Case Rep
Cook TA, Schumaecker SK, Patibandla A, Valle NJ, Summers MR.   +4 more
europepmc   +1 more source

ROMANIA’S EXTERNAL MIGRATION FROM THE PERSPECTIVE OF ACCESSION TO THE EU - INSTITUTIONAL AND BEHAVIOURAL CHALLENGES [PDF]

This paper represents a part of the authors’ contribution to a study developed under the auspices of the European Institute in Romania included in the “Pre-Accession Impact Studies - PAIS II” series, funded by a Phare project.
Daniela-Luminita Constantin, Luminita Nicolescu   +1 more
core  

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Life-Threatening Cardiogenic Shock During Chemotherapy: The Role of Mechanical Ventricular Support in Cardio-Oncology Patients. [PDF]

JACC Case Rep
Aurigemma C, Paglianiti DA, Bianchini F, Pedicino D, Saponara G, Del Buono MG, D'Aiello A, Sanna T, Trani C, Burzotta F.   +9 more
europepmc   +1 more source

Cranial anatomy of a Late Cretaceous aspidorhynchid fish (Neopterygii: Aspidorhynchiformes) from Alberta, Canada

The Anatomical Record, EarlyView.
Abstract Belonostomus longirostrisis was named for an isolated jaw fragment from freshwater Upper Cretaceous (Campanian) sediments of the Dinosaur Park Formation of Alberta, Canada. Following the description of the Albertan species, numerous isolated cranial and postcranial elements have been collected from the Dinosaur Park Formation and assigned to B.
Mondo Miyazato, Luke E. Nelson, Joshua A. Doyon, Donald B. Brinkman, Alison M. Murray   +4 more
wiley   +1 more source

Severe hypotension but not systemic inflammation or endothelial activation predicts encephalopathy in circulatory shock. [PDF]

Ann Intensive Care
Nguyen DN, Huyghens L, Nguyen TM, Schiettecatte J, Diltoer M, Cools W, De Cuyper H, Rhapsorski D, Smitz J, Zhang H.   +9 more
europepmc   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source