Results 241 to 250 of about 1,009,891 (343)

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source

Mechanical circulatory support as a cornerstone in advanced heart failure and transplantation. [PDF]

Front Cardiovasc Med
Braga M, Pinho AI, Jorde U, González-Costello J.   +3 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

A Proposed Algorithm for the Management of Patients with Cardiogenic Shock Based on Contemporary Knowledge and Gaps in Evidence. [PDF]

J Cardiovasc Dev Dis
Rammos A, Floros CD, Tzourtzos I, Stamou IE, Kalogeras P, Samara I, Siaravas KC, Bouratzis V, Bechlioulis A, Sakellariou XM, Naka KK, Michalis LK.   +11 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Integration of continuous renal replacement therapy in patients on extracorporeal life support: timing, modality, and future directions. [PDF]

Ren Fail
Hou J, Lin Z, Li J, Wang D, Hu B, Xu G.
europepmc   +1 more source

Severity or Etiology?　― Reframing Cardiogenic Shock Management in the Era of Individualized Mechanical Circulatory Support ―

Takahiro Nakashima
openalex   +2 more sources

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Successful ECMO support for cardiogenic shock induced by immune checkpoint inhibitor-associated myocarditis: a case report and literature review. [PDF]

Front Immunol
Zhang Y, Li R, Jiang Y, Sun S, Yuan Y, Shang Y, Shu H.   +6 more
europepmc   +1 more source

Optimization of cardiogenic shock therapeutics : mrtabolic, microcirculatory and inflammatory consequences of circulatory support with low or standard ECMO blood flow in a porcine model of resuscitated refrattory cardiac arrest

, 2018
Yun Luo
openalex   +1 more source