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Circulatory Shock: A Microcirculatory Defect
1985The pathophysiological defect which characterizes shock is that of perfusion failure in which blood flow to maintain the function of vital organ systems is critically reduced. As a clinical syndrome, it is characterized by protracted prostration, pallor, coldness and moistness of the skin, collapse of the superficial veins, alterations in pressure is ...
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Altered Mitochondrial Metabolism in Circulatory Shock
1977Studies of mitochondrial function after circulatory shock, hemorrhagic or endotoxic, have revealed defective oxidative metabolism in several organs, such as the liver, kidney, and the brain (1,2,3). In this comment I would like to emphasize certain important aspects of these findings.
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Heat shock factors: integrators of cell stress, development and lifespan
Nature Reviews Molecular Cell Biology, 2010Richard I Morimoto, Lea Sistonen
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Regulation of heat shock transcription factors and their roles in physiology and disease
Nature Reviews Molecular Cell Biology, 2017Rocio Gomez-Pastor, Dennis J Thiele
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Roles of heat-shock proteins in innate and adaptive immunity
Nature Reviews Immunology, 2002Pramod K Srivastava
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