Results 61 to 70 of about 1,009,891 (343)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Cardiogenic shock: incidence, survival and mechanical circulatory support usage 2007–2017-insights from a national registry

open access: yesClinical Research in Cardiology, 2020
A central element in the management of cardiogenic shock (CS) comprises mechanical circulatory support (MCS) systems to maintain cardiac output (CO). This study aims to quantify incidence, outcome and influence of MCS in CS over the last decade.
C. Lang   +11 more
semanticscholar   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker   +9 more
wiley   +1 more source

Nitroglycerin challenge identifies microcirculatory target for improved resuscitation in patients with circulatory shock

open access: yesIntensive Care Medicine Experimental
Background Circulatory shock and multi-organ failure remain major contributors to morbidity and mortality in critically ill patients and are associated with insufficient oxygen availability in the tissue. Intrinsic mechanisms to improve tissue perfusion,
Massimiliano Bertacchi   +5 more
doaj   +1 more source

How Do I Integrate Hemodynamic Variables When Managing Septic Shock? [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2016
Hemodynamic management of sepsis-induced circulatory failure is complex since this pathological state includes multiple cardiovascular derangements that can vary from patient to patient according to the degree of hypovolemia, of vascular tone depression,
Olfa Hamzaoui, Jean-Louis Teboul
doaj   +1 more source

Use of Impella 5.5 in patients with cardiogenic shock as a bridge to decision, recovery, or destination therapy

open access: yesIHJ Cardiovascular Case Reports, 2023
The overall morbidity and mortality rates of cardiogenic shock are high. The Impella 5.5 is a temporary mechanical circulatory support device that treats cardiogenic shock by supporting a failing ventricle.
Anju Bhardwaj   +6 more
doaj   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

open access: yesArthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla   +13 more
wiley   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

State of Shock: Contemporary Vasopressor and Inotrope Use in Cardiogenic Shock

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Cardiogenic shock is characterized by tissue hypoxia caused by circulatory failure arising from inadequate cardiac output. In addition to treating the pathologic process causing impaired cardiac function, prompt hemodynamic support is essential to reduce
Jason E. Bloom   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy