Results 41 to 50 of about 472,206 (302)

Numerical Investigation on Aerodynamic Performances of the Single-Stage Transonic Turbine With Various Coolant Ejection Positions and Coolant Mass Flow Rates

open access: yesFrontiers in Energy Research, 2022
The effects of film cooling holes on the suction surface and the coolant mass flow were studied in this research, which focused on load distribution and flow characteristics such as shock migration.
Jinming Zhang   +3 more
doaj   +1 more source

On the scaling of entropy viscosity in high order methods

open access: yes, 2017
In this work, we outline the entropy viscosity method and discuss how the choice of scaling influences the size of viscosity for a simple shock problem. We present examples to illustrate the performance of the entropy viscosity method under two distinct ...
C. Johnson   +12 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The baryon loading effect on relativistic astrophysical jet transport in the interstellar medium

open access: yes, 2018
The composition of the astrophysical relativistic jets remains uncertain. By kinetic particle-in-cell simulations, we show that the baryon component in the jet, or the so-called baryon loading effect (BLE), heavily affects relativistic jets transport ...
Chang, H. X.   +8 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Enhancing shock wave energy dissipation in metallosupramolecular polymer by tuning metal-imidazole coordination interactions

open access: yesPolymer Testing
The development of materials capable of shock wave energy dissipation (SWED) is critical for modern protective applications. In this study, metallosupramolecular poly(dimethylsiloxane) (PDMS) networks cross-linked with Zn2+, Cu2+, and Ni2+ ions and ...
Seungrae Cho   +6 more
doaj   +1 more source

Effect of Repeated Thermal Shock on Mechanical Properties of ZrB2-SiC-BN Ceramic Composites

open access: yesThe Scientific World Journal, 2014
ZrB2-20 vol.% SiC-10 vol.% h-BN (particles) ceramic composites (ZSB) were fabricated by hot pressing under inert gas protected. ZSB samples with mean size 75 × 55 × 40 mm3 were heated using current heating method and then cooled down to low temperature ...
Gang Li, Hongbo Chen
doaj   +1 more source

A numerical model of parsec scale SSC morphologies and their radio emission [PDF]

open access: yes, 2016
In current models for jets of AGNs and their emission a shortcoming in the description and understanding of the connection between the largest and smallest scales exists.
Richter, Stephan, Spanier, Felix
core   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Experimental Study of the Load-Transfer Law and Shock Environment of a Pipe–Float System

open access: yesJournal of Marine Science and Engineering
To study the load-transfer law and shock environment of a pipe–float system, an experimental model was designed, manufactured, and installed on a floating shock platform.
Miaoran Li   +7 more
doaj   +1 more source

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