Results 51 to 60 of about 471,315 (302)

The baryon loading effect on relativistic astrophysical jet transport in the interstellar medium

, 2018
The composition of the astrophysical relativistic jets remains uncertain. By kinetic particle-in-cell simulations, we show that the baryon component in the jet, or the so-called baryon loading effect (BLE), heavily affects relativistic jets transport ...
Chang, H. X., He, X. T., Qiao, B., Xu, Z., Yao, W. P., Zhang, H., Zhao, Z. H., Zhou, C. T., Zhu, S. P.   +8 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Integrative analyses identify the mechanism by which HSPA9 influences glioma energy metabolism

Oncologie
Heat shock protein family A (Hsp70) member 9 (HSPA9) is a mitochondrial chaperone protein that belongs to the heat shock protein 70 family. HSPA9 is expressed across various malignancies.
He Wenying, Zhang QingHua, Xie Jixin, Wu Fang, Wang Lijuan, Wang Libin   +5 more
doaj   +1 more source

Shock wave dynamics in nanoporous tungsten and molybdenum via molecular dynamics simulations: Insights into thermodynamic and structural evolution

Journal of Materials Research and Technology
Nanoporous tungsten (NP–W) and molybdenum (NP–Mo) are of great interest in aerospace and nuclear fusion/fission reactor industrial sections. Molecular dynamics (MD) simulations are employed for understanding the influences of shock velocity and relative ...
Yiqun Hu, Zhenhai Li, Xiumin Xu, Yuhang Zhang, Re Xia   +4 more
doaj   +1 more source

Shock Vibration Control of SDOF Systems with Tubular Linear Eddy Current Dampers

Applied Sciences, 2023
The nonlinear dynamic characteristic of a tubular linear eddy current damper (TLECD) and the transient responses to shock excitations of a single-degree-of-freedom (SDOF) system with the TLECD are studied. First, the nonlinear force-velocity relationship
Yida Pu, Zhiwen Huang, Hongyi Zhang, Xugang Hua, Yousheng Xu   +4 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

A numerical model of parsec scale SSC morphologies and their radio emission [PDF]

, 2016
In current models for jets of AGNs and their emission a shortcoming in the description and understanding of the connection between the largest and smallest scales exists.
Richter, Stephan, Spanier, Felix
core   +3 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source