Results 41 to 50 of about 287,191 (265)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Bioengineered human blood vessels to treat hospital-acquired vascular complications

Journal of Vascular Surgery Cases and Innovative Techniques
Background: Complications of vascular surgery and vascular procedures, including iatrogenic injuries, planned oncological tumor resections, and steal syndrome after arteriovenous access placement, are increasingly common in modern medical care ...
YingWei Lum, MD, Ernest E. Moore, MD, Rishi Kundi, MD, Jonathan Morrison, MD, Jamie T. Shores, MD, Laura E. Niklason, MD, PhD, Shamik Parikh, MD   +6 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

The Efficacy of Antibacterial Therapy in Patients with Sepsis and Septic Shock

Український журнал клінічної хірургії
Objective. To analyze the effectiveness of various methods of antibacterial therapy in patients with sepsis and septic shock. Materials and methods.
S. D. Shapoval
doaj   +1 more source

Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock

Frontiers in Pediatrics, 2018
Shock in newborn infants has unique etiopathologic origins that require careful assessment to direct specific interventions. Early diagnosis is key to successful management.
Yogen Singh, Yogen Singh, Anup C. Katheria, Anup C. Katheria, Farha Vora   +4 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Efficacy of radial extracorporeal shock wave therapy compared with botulinum toxin type A injection in treatment of lower extremity spasticity in subjects with cerebral palsy: A randomized, controlled, cross-over study

Journal of Rehabilitation Medicine, 2020
Objectives: To investigate whether botulinum toxin type A (BTX-A) injection is more effective than radial extracorporeal shock wave therapy in reducing plantar flexor muscle spasticity in subjects with cerebral palsy. Methods: A total of 68 subjects with
Xavier Vidal, Joan Martí-Fàbregas, Olga Canet, Marta Roqué, Antoni Morral, Miriam Tur, Christoph Schmitz, Mercè Sitjà-Rabert   +7 more
doaj   +1 more source

A comparative study of the efficacy of radial and focused shock wave therapy for tennis elbow depending on symptom duration

Archives of Medical Science, 2020
Introduction In physical therapy, the duration and severity of pain complaints determine the choice of an appropriate physical agent and parameters needed.
Magdalena Stania, Barbara Król, Andrzej Franek, Edward Błaszczak, Paweł Dolibog, Anna Polak, Patrycja Dolibog, Jacek Durmała, Piotr Król   +8 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Revisiting nitrates use in pre-shock state of contemporary cardiogenic shock classification

Frontiers in Cardiovascular Medicine
Patients at each shock stage may behave and present differently with a spectrum of shock severity and adverse outcomes. Shock severity, shock aetiology, and several factors should be integrated in management decision-making.
Rasha Kaddoura, Ashfaq Patel, Abdul Rahman Arabi   +2 more
doaj   +1 more source