Results 41 to 50 of about 11,785,126 (289)

Primal-dual simplex method for shooting

open access: yesElectronic Notes in Discrete Mathematics, 2010
Abstract Gomory [R.E. Gomory, Some polyhedra related to combinatorial problems, Linear Algebra and its Applications 2 (1969), 451–558] solved the cyclic group problem by a dynamic programming algorithm. We discuss its complexity and introduce a (fractional) cutting plane algorithm as an alternative algorithm.
Sangho Shim   +2 more
openaire   +2 more sources

The linearization methods as a basis to derive the relaxation and the shooting methods

open access: yesCoRR, 2020
This chapter investigates numerical solution of nonlinear two-point boundary value problems. It establishes a connection between three important, seemingly unrelated, classes of iterative methods, namely: the linearization methods, the relaxation methods (finite difference methods), and the shooting methods. It has recently been demonstrated that using
Faragó, István, Filipov, Stefan M.
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

The best angle correction of basketball shooting based on the fusion of time series features and dual CNN

open access: yesEgyptian Informatics Journal
The best shooting angle correction of basketball based on intelligent image analysis is an important branch of the development of intelligent sports. However, the current method is limited by the variability of the shape base, ignoring dynamic features ...
Meicai Xiao
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni   +4 more
wiley   +1 more source

The shooting method applied to a cyclic inequality [PDF]

open access: yesMathematics of Computation, 1980
It is known that the cyclic sum \[ S n ( x ) = ∑ i = 1 i = n x ...
openaire   +2 more sources

Clinical Validation of Artificial Intelligence (AI)‐based Cartilage Segmentation Predicting Knee Replacement

open access: yesArthritis Care &Research, Accepted Article.
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein   +3 more
wiley   +1 more source

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