Results 181 to 190 of about 4,473 (248)

Navigating Evidence Standards: Stakeholder Perspectives on External Controls and Randomization in Cancer Trials

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
While historically the ‘gold standard,’ the role of large‐scale RCTs is being increasingly challenged in the contemporary oncology research era. External controls represent an alternate method for generating evidence, though the perspectives of key stakeholders regarding their role in oncology are not well known.
Sarah E. Heynemann   +5 more
wiley   +1 more source

Rulers on the road: Itinerant rule in the Holy Roman Empire, AD 919–1519

open access: yesAmerican Journal of Political Science, EarlyView.
Abstract Itinerant rule, rule exercised through traveling, was a common yet insufficiently researched, premodern form of governance. Studying the determinants of ruler itineraries in the Holy Roman Empire, AD 919–1519, we argue that rulers' visits targeted “marginal” elites.
Carl Müller‐Crepon   +3 more
wiley   +1 more source

Investigations on the Performances of Corn Starch/PBAT Blends. [PDF]

open access: yesPolymers (Basel)
Zhao W, Qiu R, Fang M, Lei W, Chen Y.
europepmc   +1 more source

Expanding the Taxonomy of Ethical Issues in Surgical Innovation

open access: yesBioethics, EarlyView.
ABSTRACT Surgical innovation poses significant ethical challenges. Previous work has grouped these challenges under four categories: potential harms to patients; compromised informed consent; unfair allocation of healthcare resources; and conflicts of interest. We argue that recent technological developments in surgery warrant the addition of three new
Jane Johnson   +2 more
wiley   +1 more source

Out in the cold? A review of Early Middle Palaeolithic settlements in northern Central Europe, age data and geological preconditions for site formation and preservation

open access: yesBoreas, EarlyView.
The characteristics of settlement of Neanderthals in northern Central Europe during the earlier phases of the Middle Palaeolithic (Marine Isotope Stage 8–6) have been a matter of debate for decades, specifically regarding the population dynamics at such latitudes during the coldest phases. In this paper, we review the known archaeological record of the
Gianpiero Di Maida   +5 more
wiley   +1 more source

A Simple Grid‐Maps Pipeline: Restructured, Accelerated and Upgraded

open access: yesComputer Graphics Forum, EarlyView.
Abstract Grid maps – spatially arranged small multiples – are a powerful tool to show complex geospatial data. Meulemans et al. (2020) introduced a pipeline for computing high‐quality grid maps that are shaped roughly according to their containing geographic outlines.
W. Meulemans
wiley   +1 more source

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