Results 91 to 100 of about 8,709 (263)
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Research on Load Forecasting Based on Bayesian Optimized CNN-LSTM Neural Network
With the high penetration of renewable energy integration and massive user participation in electricity markets, traditional short-term load forecasting methods exhibit limitations in both adaptability and prediction accuracy.
Pengyang Duan +6 more
doaj +1 more source
Multi-horizon short-term load forecasting using hybrid of LSTM and modified split convolution. [PDF]
Ullah I +5 more
europepmc +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Short-term load forecasting system based on sliding fuzzy granulation and equilibrium optimizer. [PDF]
Li S, Wang J, Zhang H, Liang Y.
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Short-Term Load Forecasting Based on EEMD-WOA-LSTM Combination Model. [PDF]
Shao L, Guo Q, Li C, Li J, Yan H.
europepmc +1 more source

