Results 41 to 50 of about 8,161 (262)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Short-term load forecasting using Theta method [PDF]

open access: yesE3S Web of Conferences, 2019
The Theta method attracted the attention of researchers and practitioners in recent years due to its simplicity and superior forecasting accuracy. Its performance has been confirmed by many empirical studies as well as forecasting competitions.
Dudek Grzegorz
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Fuzzy short-term electric load forecasting

open access: yesInternational Journal of Electrical Power & Energy Systems, 2004
Load forecasting is necessary for economic generation of power, economic allocation between plants (unit commitment scheduling), maintenance scheduling, and for system security such as peak load shaving by power interchange with interconnected utilities. In this paper a fuzzy linear regression model for summer and winter seasons is developed.
A.M. Al-Kandari   +2 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Short- and Very Short-Term Firm-Level Load Forecasting for Warehouses: A Comparison of Machine Learning and Deep Learning Models

open access: yesEnergies, 2022
Commercial buildings are a significant consumer of energy worldwide. Logistics facilities, and specifically warehouses, are a common building type which remain under-researched in the demand-side energy forecasting literature.
Andrea Maria N. C. Ribeiro   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research on short-term power load forecasting based on deep reinforcement learning with multiple intelligences

open access: yesEAI Endorsed Transactions on Energy Web
A reliable supply of power systems is critical for industry, commerce, and residential life. Improving the accuracy and reliability of short-term electricity load forecasting plays a crucial role in ensuring the satisfaction of electricity demand and ...
Tianyun Luo   +5 more
doaj   +1 more source

Power Load Prediction Based on Fractal Theory

open access: yesAdvances in Mathematical Physics, 2015
The basic theories of load forecasting on the power system are summarized. Fractal theory, which is a new algorithm applied to load forecasting, is introduced.
Liang Jian-Kai   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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