Results 61 to 70 of about 3,183,655 (317)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The Structure of Working Memory and Its Relationship with Intelligence in Japanese Children

Journal of Intelligence, 2023
There is a host of research on the structure of working memory (WM) and its relationship with intelligence in adults, but only a few studies have involved children.
Yoshifumi Ikeda, Yosuke Kita, Yuhei Oi, Hideyuki Okuzumi, Silvia Lanfranchi, Francesca Pulina, Irene Cristina Mammarella, Katie Allen, David Giofrè   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multiple decomposition‐aided long short‐term memory network for enhanced short‐term wind power forecasting

IET Renewable Power Generation
With the increasing penetration of grid‐scale wind energy systems, accurate wind power forecasting is critical to optimizing their integration into the power system, ensuring operational reliability, and enabling efficient system asset utilization ...
Mehmet Balci, Emrah Dokur, Ugur Yuzgec, Nuh Erdogan   +3 more
doaj   +1 more source

Improved LSTM Method of Predicting Cryptocurrency Price Using Short-Term Data

IJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2023
As cryptocurrencies develop, it cannot be denied that crypto prices are volatile. One of the influencing factors is the increasing volume of transactions which attracts the interest of researchers to conduct research in developing coin price predictions ...
Risna Sari, Kusrini Kusrini, Tonny Hidayat, Theofanis Orphanoudakis   +3 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Aircraft Gearbox Fault Diagnosis System: An Approach based on Deep Learning Techniques

Journal of Intelligent Systems, 2020
Gearbox is one of the vital components in aircraft engines. If any small damage to gearbox, it can cause the breakdown of aircraft engine. Thus it is significant to study fault diagnosis in gearbox system.
Mallikarjuna P B, Sreenatha M, Manjunath S, Kundur Niranjan C   +3 more
doaj   +1 more source

Evidence Against Novelty-Gated Encoding in Serial Recall

Journal of Cognition, 2022
Novelty-gated encoding is the assumption that events are encoded more strongly into memory when they are more novel in comparison to previously encoded events. It is a core assumption of the SOB model of serial recall (Farrell & Lewandowsky, 2002).
Klaus Oberauer, Simon Farrell, Christopher Jarrold, Marcel Niklaus   +3 more
doaj   +1 more source