Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Short-term prediction of COVID-19 spread using grey rolling model optimized by particle swarm optimization. [PDF]
Ceylan Z.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Short term prediction of photovoltaic power with time embedding temporal convolutional networks. [PDF]
Wang J, Li G, Gu J, Xu Z, Chen X, Wei J.
europepmc +1 more source
A Short-Term Prediction Model at the Early Stage of the COVID-19 Pandemic Based on Multisource Urban Data. [PDF]
Wang R +5 more
europepmc +1 more source
Short-Term Predictions of Oceanic Drift [PDF]
Kai Christensen +4 more
openaire +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Development and Internal Validation of Machine-Learning Models for Short-Term Prediction of Day-to-Day Home Blood Pressure Variability Using IoT-Based Environmental and Activity Data: Protocol for the AURA-BPV Study. [PDF]
Nakao YM, Takayama A, Kawakami K.
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Combining semiparametric and machine learning approaches for short-term prediction of satellite clock bias. [PDF]
Jin L +5 more
europepmc +1 more source

