Results 191 to 200 of about 10,094,639 (283)

Integrated assessment of rifampicin‐mediated induction of transporters and drug‐metabolizing enzymes in a long‐term human liver tissue chip system

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Rifampicin is a prototypical clinical inducer used in drug–drug interaction (DDI) studies. However, the clinical relevance and predictability of rifampicin‐mediated hepatic transporter induction remain poorly defined. Conventional hepatocyte culture models fail to capture clinically relevant regulation of transporters and drug‐metabolizing enzymes ...
Mattie E. Hartauer   +9 more
wiley   +1 more source

Memory-Augmented Spatio-Temporal Transformer for Robust Traffic Flow Forecasting. [PDF]

open access: yesBiomimetics (Basel)
Hu P   +6 more
europepmc   +1 more source

A Dynamic Business Modeling Approach to Port Sustainability: The Western Sicily Port Authority Case

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Ports are critical nodes in global trade and economic development, yet they generate substantial environmental and social externalities—including greenhouse gas emissions, air, noise, and water pollution, and adverse impacts on host communities—that demand integrated and forward‐looking governance.
Martina Vivoli   +3 more
wiley   +1 more source

Do Firms Disclose Financially Material ESG Risks? Evidence From Japanese Food and Beverage Firms Using a Text Match Pretrained Transformer

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study develops a financial materiality‐oriented measure of ESG disclosure and examines how sustainability disclosures respond to evolving regulatory frameworks. Focusing on listed food and beverage firms in Japan from 2020 to 2024, we apply the Text Match Pretrained Transformer (TMPT) to assess the semantic relevance between disclosures ...
Siyu Shen   +5 more
wiley   +1 more source

Fluid‐induced slip on a rate‐and‐state fault during co‐ and post‐injection: The interplay of fluid pressure diffusion and poroelastic stress

open access: yesDeep Underground Science and Engineering, EarlyView.
Fault slip can occur ahead of the injection pressure front due to poroelastic stress. Our model captures the interaction of pressure, stress, and friction, providing new insights into injection‐induced seismicity and post‐injection fault slip. Shut‐in operations can either mitigate or accelerate seismic events depending on fault conditions and ...
Qifeng Xie, Lei Wang, Qi Li
wiley   +1 more source

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

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