Rifampicin is a prototypical clinical inducer used in drug–drug interaction (DDI) studies. However, the clinical relevance and predictability of rifampicin‐mediated hepatic transporter induction remain poorly defined. Conventional hepatocyte culture models fail to capture clinically relevant regulation of transporters and drug‐metabolizing enzymes ...
Mattie E. Hartauer +9 more
wiley +1 more source
Memory-Augmented Spatio-Temporal Transformer for Robust Traffic Flow Forecasting. [PDF]
Hu P +6 more
europepmc +1 more source
A Dynamic Business Modeling Approach to Port Sustainability: The Western Sicily Port Authority Case
ABSTRACT Ports are critical nodes in global trade and economic development, yet they generate substantial environmental and social externalities—including greenhouse gas emissions, air, noise, and water pollution, and adverse impacts on host communities—that demand integrated and forward‐looking governance.
Martina Vivoli +3 more
wiley +1 more source
Multi-Granular Embedding and Hybrid Encoder-Decoder Architecture with Temporal Linear Regression Bypass for Sensor-Based Time Series Forecasting in Smart Infrastructure. [PDF]
Cheng HY, Lin HH, Jiang CL, Yu CC.
europepmc +1 more source
ABSTRACT This study develops a financial materiality‐oriented measure of ESG disclosure and examines how sustainability disclosures respond to evolving regulatory frameworks. Focusing on listed food and beverage firms in Japan from 2020 to 2024, we apply the Text Match Pretrained Transformer (TMPT) to assess the semantic relevance between disclosures ...
Siyu Shen +5 more
wiley +1 more source
Beyond static snapshots: gated recurrent units and graph attention networks for smarter multi-agent traffic control. [PDF]
Mohita, Singh SD, Subitha D, Kavitha JC.
europepmc +1 more source
Fault slip can occur ahead of the injection pressure front due to poroelastic stress. Our model captures the interaction of pressure, stress, and friction, providing new insights into injection‐induced seismicity and post‐injection fault slip. Shut‐in operations can either mitigate or accelerate seismic events depending on fault conditions and ...
Qifeng Xie, Lei Wang, Qi Li
wiley +1 more source
GADEF-Net: A heterogeneity-aware dual-graph framework for robust multimodal traffic forecasting. [PDF]
Wang X +5 more
europepmc +1 more source
Secretopathies emerge as a new class of neurocristopathies
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
A Sensor-Data-Driven Proactive Accident Detection and Traffic Prediction Method Based on Lane-Level Grid Partitioning and a Three-Dimensional Markov Model. [PDF]
Zeng M, Chen H.
europepmc +1 more source

