Results 91 to 100 of about 288,419 (289)

Short Duration Transient Visual Evoked Potentials in Glaucomatous Eyes [PDF]

, 2012
Purpose: To investigate the correlation between structural and functional damage in patients with asymmetric glaucoma using a newly developed short duration transient visual evoked potential (SD-tVEP) device.Methods: Twenty-five patients with visual ...
De Moraes, Carlos Gustavo V., Prata, Tiago Santos [UNIFESP], Ritch, Robert, Valerie Trubnik, Trubnik, Valerie, Peter Derr, Tiago Santos Prata, Derr, Peter, Verônica C. Lima, Liebmann, Jeffrey M., Jeffrey M. Liebmann, Robert Ritch, Carlos Gustavo V. De Moraes, Lima, Veronica C. [UNIFESP], Tello, Celso, Celso Tello   +15 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Short-term effects of intravitreal dexamethasone implant (OZURDEX®) on choroidal thickness in patients with naive branch retinal vein occlusion [PDF]

, 2016
Purpose: The objective of this study was to evaluate subfoveal choroidal thickness (SFCT) using enhanced depth imaging optical coherence tomography (EDI-OCT) in patients with naïve branch retinal vein occlusion (BRVO) before and after intravitreal ...
Necati Duru (5763806), Bedirhan Alabay (5763815), Orhan Altunel (5762945), Burhan Baskan (5763812), Mustafa Atas (5763818), Hasan Basri Arifoglu (5763800)   +5 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Seeing Compassion Through Students' Eyes [PDF]

This chapter draws upon a small-scale qualitative study, funded by the UK Society for Research into Higher Education (SRHE), which addressed the question: What does compassionate learning and teaching look like when viewed through students’ eyes?
Bonaparte, B., Waddington, K.
core   +1 more source

mTD progression rate in all eyes, WEM-d low, WEM-d high, WEM-t short, and WEM-t long subgroups. [PDF]

, 2018
mTD progression rate in all eyes, WEM-d low, WEM-d high, WEM-t short, and WEM-t long subgroups.
Yoshiaki Kiuchi (80320), Masato Matsuura (3043017), Shuichiro Aoki (5778473), Yoshitaka Nakao (816294), Shunsuke Nakakura (556508), Hiroshi Murata (387321), Ryo Asaoka (387326)   +6 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Face Inversion Disproportionately Disrupts Detection of Vertical versus Horizontal, Not Long-Range versus Short-Range, Spatial Relations

i-Perception, 2011
Presenting a face inverted disrupts sensitivity to the spacing between the features. Recent evidence suggests that inversion disproportionately affects sensitivity to vertical over horizontal changes in eye position.
Kate Crookes, William G. Hayward
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source