Results 61 to 70 of about 482,946 (280)

The Sleep Condition Indicator: a clinical screening tool to evaluate insomnia disorder [PDF]

, 2014
Objective: Describe the development and psychometric validation of a brief scale (the Sleep Condition Indicator (SCI)) to evaluate insomnia disorder in everyday clinical practice.<p></p> Design: The SCI was evaluated across five study ...
Cape, John, Espie, Colin A., Fleming, Leanne, Gardani, Maria, Hames, Peter, Kyle, Simon D.   +5 more
core   +5 more sources

Short sleep duration and obesity: the role of emotional stress and sleep disturbances [PDF]

International Journal of Obesity, 2008
Many epidemiologic studies have reported that obesity is associated with short sleep duration. How the degree of obesity or other clinical characteristics of the obese individuals, such as sleep disturbances or emotional stress, define this relation is not known.We studied a random sample of 1300 middle-aged men and women from the Penn State Cohort in ...
Vgontzas, A.N., Lin, H.-M., Papaliaga, M., Calhoun, S., Vela-Bueno, A., Chrousos, G.P., Bixler, E.O.   +6 more
openaire   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Factors affecting the sleep of one-year-olds : a pilot study using objective monitoring of New Zealand infants : a thesis presented in partial fulfilment of the requirements of the degree of Master of Science in Psychology at Massey University, Wellington, New Zealand [PDF]

, 2009
Sleep takes time to mature and in infancy the structure and cycle of sleep differs greatly to that of adults. Data concerning normative sleep of infants is lacking due to few studies using objective measures.
Gibson, Rosemary H
core  

Maternal and paternal sleep during pregnancy in the Child-sleep birth cohort [PDF]

, 2017
Study objectives: Maternal and paternal sleep insufficiency during pregnancy appears to be a risk factor for health and wellbeing in young families. Here, we evaluated the prevalence of sleep insufficiency and symptoms of insomnia during pregnancy (at ...
Kylliainen, Anneli, Paavonen, E. Juulia, Paunio, Tiina, Polkki, Pirjo, Porkka-Heiskanen, Tarja, Saarenpaa-Heikkila, Outi   +5 more
core   +1 more source

Associations of self-reported sleep duration and sleep difficulties with cardiometabolic risk factors among U.S.-born and foreign-born black adults in the United States: NHANES 2005-2016

Sleep Epidemiology, 2022
Self-reported sleep duration and poor sleep quality are understudied determinants of cardiometabolic (CMB) health among Black populations. We conducted a cross-sectional analysis among 4,974 U.S.-born and 615 Foreign-born Black adults using a U.S. sample
Sheroi Johnson, Rukkayya Labaran, Dayna A. Johnson   +2 more
doaj   +1 more source

Asian-White disparities in short sleep duration by industry of employment and occupation in the US: a cross-sectional study [PDF]

, 2014
Background: Although short sleep is associated with an increased risk of morbidity as well as mortality and has been shown to vary by industry of employment and occupation, little is known about the relationship between work and sleep among Asian ...
Hu, Frank B, Jackson, Chandra L, Juon, Hee-Soon, Kawachi, Ichiro, Redline, Susan   +4 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source